Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847597 | 0.82 | EGLN1 (0.58) | EGLN1LMNASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL3371417 | 0.82 | EGLN1 (1.00) | EGLN1KDM4ELMNAALDH1A1HPGD | |
| SCHEMBL8847516 | 0.80 | KDM4E (0.58) | EGLN1KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8848249 | 0.80 | KDM4E (0.59) | EGLN1KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL9823339 | 0.78 | EGLN1 (0.53) | EGLN1KDM4ELMNAALDH1A1 | |
| SCHEMBL19327449 | 0.77 | LMNA (0.54) | EGLN1KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6648649 | 0.76 | KDM4E (0.54) | EGLN1KDM4ELMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1422234 | 0.74 | LMNA (0.74) | KDM4ELMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11392035 | 0.73 | KDM4E (0.63) | KDM4ELMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL22940438 | 0.73 | PDE10A (0.54) | EGLN1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |
| US-5620968-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1997-04-15 | — | — | US | disclosed |
| US-5527792-A | CARBA- AND OXACEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1996-06-18 | — | — | US | disclosed |
| US-5525599-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1996-06-11 | — | — | US | disclosed |