Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365480 | 0.79 | SMN1; SMN2 (0.67) | TSHRSMN1; SMN2NPSR1NR4A2HPGD | |
| SCHEMBL6248551 | 0.74 | TSHR (0.69) | TSHRSRD5A2ALDH1A1 | |
| SCHEMBL560291 | 0.73 | HSP90AA1 (0.58) | HPGDMEN1KMT2AELANECTSG | |
| SCHEMBL29087479 | 0.72 | TSHR (0.54) | TSHRSMN1; SMN2RXRASRD5A2NPC1 | |
| SCHEMBL27986872 | 0.71 | TSHR (0.69) | TSHRSMN1; SMN2HPGDRXRARXRB | |
| SCHEMBL69041 | 0.71 | TSHR (1.00) | TSHRHPGDSRD5A2KDM4EALDH1A1 | |
| SCHEMBL11464000 | 0.71 | TSHR (0.50) | TSHRSMN1; SMN2NR4A2SRD5A2NPC1 | |
| SCHEMBL2034240 | 0.70 | CYP2A6 (0.61) | TSHRSMN1; SMN2NPSR1NR4A2HPGD | |
| SCHEMBL20370925 | 0.70 | TSHR (0.63) | TSHRSMN1; SMN2SRD5A2 | |
| Benzoic Acid SCHEMBL9161402 | 0.69 | TSHR (0.61) | TSHRSMN1; SMN2NR4A2HPGDRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2159228-A1 | Amphiphilic solid support | Polymer Laboratories Limited (GB) | 2010-03-03 | — | — | EP | disclosed |