Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL27450694 | 0.82 | RAB9A (0.50) | L3MBTL1RAB9ANPC1KMT2ASMN1; SMN2 | |
| SCHEMBL8637118 | 0.79 | ALDH1A1 (0.61) | L3MBTL1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL6299177 | 0.79 | KEAP1 (0.64) | KMT2AMEN1GFER | |
| SCHEMBL3814505 | 0.78 | MEN1 (0.50) | L3MBTL1KMT2AMAOBMEN1KDM4E | |
| SCHEMBL3357458 | 0.78 | CALM1 (0.55) | KMT2AMEN1LMNAALDH1A1HIF1A | |
| SCHEMBL9018903 | 0.78 | TSHR (0.50) | TSHRRAB9ANPC1SNCAMAOB | |
| SCHEMBL26134815 | 0.78 | TSHR (0.69) | TSHRL3MBTL1LMNAALDH1A1SRD5A2 | |
| SCHEMBL4423210 | 0.78 | SIGMAR1 (0.53) | KMT2AMEN1LMNAALDH1A1HIF1A | |
| SCHEMBL28066556 | 0.76 | KMT2A (0.58) | TSHRL3MBTL1RAB9ANPC1KMT2A | |
| SCHEMBL19757434 | 0.76 | HSD17B3 (0.54) | L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55141477-A | — | — | None | — | — | JP | disclosed |
| JP-S55141477-A | PREPARATION OF 3,4-DISUBSTITUTED-1,2,5-THIADIAZOLE | TASHIRO MASASHI | 1980-11-05 | — | — | JP | disclosed |