Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 15/20 | 1.00 |
| ▸ | PTGER3 | P43115 | 6/20 | 1.00 |
| ▸ | TBXA2R | P21731 | 3/20 | 1.00 |
| ▸ | PTGER1 | P34995 | 2/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 0.82 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.82 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.68 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13426514 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL20573392 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL13399765 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL3390323 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL3368364 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL13399717 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL3368370 | 1.00 | PTGFR (1.00) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| Flunoprost SCHEMBL1230709 | 0.92 | PTGFR (0.84) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL11342852 | 0.92 | PTGFR (0.84) | PTGFRPTGER3TBXA2RPTGER1THRB | |
| SCHEMBL10988947 | 0.91 | PTGFR (0.83) | PTGFRPTGER3TBXA2RPTGER1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | claimed |
| US-8722739-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-8623918-B2 | Amino acid salts of prostaglandins | NOVAER HOLDINGS, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-8470882-B2 | — | — | 2013-06-25 | — | — | US | disclosed |
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | NOVAER HOLDINGS, INC. | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105771-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | PTGFR 7/4885PTGER3 16/4885TBXA2R 22/4885 |
| US-20100105775-A1 | AMINO ACID SALTS OF PROSTAGLANDINS | PTGIS, PTGES, PTGIR | PTGFR 7/4885PTGER3 16/4885TBXA2R 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.