Flunoprost

Flunoprost

SCHEMBL1230709

O=C(O)CCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)COc2ccccc2)[C@H](O)C[C@H]1F

nearest known ligand 0.84

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PTGFR P43088 14/20 0.84
PTGER3 P43115 6/20 0.84
TBXA2R P21731 3/20 0.84
PTGER1 P34995 2/20 0.84
THRB P10828 1/20 0.70
PTGER2 P43116 1/20 0.70
RAB9A P51151 1/20 0.59
ABCC4 O15439 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13399765 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL3368368 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL3390323 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL13426514 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL3368364 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL20573392 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL13399717 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL3368370 0.92 PTGFR (1.00) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL9691381 0.85 PTGFR (0.61) PTGFRPTGER3TBXA2RPTGER1THRB
SCHEMBL11342852 0.83 PTGFR (0.84) PTGFRPTGER3TBXA2RPTGER1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9016221-B2 Surface topographies for non-toxic bioadhesion control UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2015-04-28 US claimed
US-20100226943-A1 SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL UNIVERSITY OF FLORIDA (US) 2010-09-09 US claimed
CN-101330905-A Freeze-drying process and products obtained thereby SCIDOSE LLC (US) 2008-12-24 CN claimed
EP-1954244-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY Scidose, Llc (US) 2008-08-13 EP claimed
WO-2007061529-A1 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. (US) 2007-05-31 WO claimed
US-20070116729-A1 Lyophilization process and products obtained thereby SCIDOSE LLC 2007-05-24 US claimed
EP-3782649-B1 BIODEGRADABLE POLYETHYLENE GLYCOL BASED WATER-INSOLUBLE HYDROGELS ASCENDIS PHARMA AS (DK) 2025-05-14 EP disclosed
CN-119947711-A Organogels for sustained drug delivery, methods of preparation and uses thereof 视尔普斯眼科公司 2025-05-06 CN disclosed
CN-119424655-A Drug delivery system for treating glaucoma or ocular hypertension 细胞疗法有限责任公司 2025-02-14 CN disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 US disclosed
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels ASCENDIS PHARMA A/S (DK) 2023-04-20 US disclosed
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels ASCENDIS PHARMA A/S (DE) 2023-01-24 US disclosed
US-20040141922-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2004-07-22 US disclosed
US-6680047-B2 FOR USE IN ULTRASOUND IMAGING, CONTRAST AGENTS AMERSHAM HEALTH AS (NO) 2004-01-20 US disclosed
US-20020102215-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-20020102217-A1 Diagnostic/therapeutic agents NYCOMED IMAGING AS 2002-08-01 US disclosed
US-6331289-B1 ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED NYCOMED IMAGING AS (NO) 2001-12-18 US disclosed
US-6264917-B1 MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT NYCOMED IMAGING AS (NO) 2001-07-24 US disclosed
US-6261537-B1 TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES NYCOMED IMAGING AS (NO) 2001-07-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040141922-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 PTGFR 486/4885PTGER3 2707/4885TBXA2R 510/4885
US-20230123784-A1 Biodegradable Polyethylene Glycol Based Water-Insoluble Hydrogels PLG, PHYKPL, PLOD3 PTGFR 194/4885PTGER3 576/4885TBXA2R 4066/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 PTGFR 2424/4885PTGER3 3521/4885TBXA2R 943/4885
US-11559482-B2 Biodegradable polyethylene glycol based water-insoluble hydrogels PLG, PHYKPL, PLOD3 PTGFR 194/4885PTGER3 576/4885TBXA2R 4066/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 PTGFR 2424/4885PTGER3 3521/4885TBXA2R 943/4885
US-20020102215-A1 Diagnostic/therapeutic agents BID, FUS, FABP1 PTGFR 598/4885PTGER3 2930/4885TBXA2R 705/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.