SCHEMBL3368533

SCHEMBL3368533

CCCCCOC[C@H](CO)OCc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.45
TLR2 O60603 8/20 0.44
CETP P11597 3/20 0.41
CNR1 P21554 4/20 0.40
CNR2 P34972 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 1/20 0.40
TSHR P16473 1/20 0.40
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9637838 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL385333 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL15070695 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL25077516 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL1096268 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL25227181 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL9470027 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL25227184 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL10043031 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2
SCHEMBL3283279 0.99 USP2 (0.47) USP2TLR2CETPCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2012-07-05 US disclosed
US-8076520-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2011-12-13 US disclosed
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2010-11-04 US disclosed
US-7709464-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E. V. (DE) 2010-05-04 US disclosed
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2009-02-05 US disclosed
US-7351428-B2 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2008-04-01 US disclosed
US-20040213836-A1 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2004-10-28 US disclosed
US-20030053978-A1 Phosphatidyl oligoglycerols MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. 2003-03-20 US disclosed
US-20020090383-A1 Compounds which increase the survival duration of liposomes MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2002-07-11 US disclosed
US-6413543-B1 DRUG DELIVERY MAX-PLANCK-GESSELSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) 2002-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040213836-A1 Phosphatidyl oligoglycerols PHOSPHO1, SGMS1, SGMS2 USP2 2036/4885TLR2 1775/4885CETP 120/4885
US-20030053978-A1 Phosphatidyl oligoglycerols PHOSPHO1, SGMS1, SGMS2 USP2 2339/4885TLR2 2025/4885CETP 150/4885
US-20020090383-A1 Compounds which increase the survival duration of liposomes VEGFA, MCL1, LIPA USP2 1898/4885TLR2 2810/4885CETP 76/4885
US-20100280282-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG USP2 2163/4885TLR2 1912/4885CETP 114/4885
US-20120172631-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG USP2 2163/4885TLR2 1912/4885CETP 114/4885
US-20090035358-A1 PHOSPHATIDYL OLIGOGLYCEROLS PHOSPHO1, SGMS2, LIPG USP2 2163/4885TLR2 1912/4885CETP 114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.