SCHEMBL385333

SCHEMBL385333

CCCCCCCCCCCCCCCCCCOC[C@H](CO)OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
TLR2 O60603 8/20 0.45
CETP P11597 3/20 0.43
CNR2 P34972 4/20 0.42
CNR1 P21554 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3283279 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL9470027 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL9637838 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL10043031 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL25227184 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL1096268 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL25077516 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL15070695 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL25227181 1.00 USP2 (0.47) USP2TLR2CETPCNR2CNR1
SCHEMBL3368533 0.99 USP2 (0.45) USP2TLR2CETPCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080221061-A1 Lung-Targeted Drugs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-09-11 US claimed
CN-122080069-A Phospholipid compounds and uses thereof 2026-05-26 CN disclosed
US-20260109724-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES INC (US) 2026-04-23 US disclosed
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-04-07 US disclosed
US-12521397-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-01-13 US disclosed
US-12473314-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2025-11-18 US disclosed
US-12350274-B2 Nucleotide analogs THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-08 US disclosed
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
EP-4537828-A2 PHOSPHOLIPID COMPOUNDS AND USES THEREOF Gilead Sciences, Inc. (US) 2025-04-16 EP disclosed
CN-115175735-B Antiviral compounds 吉利德科学公司 2025-03-04 CN disclosed
WO-1996039831-A1 PRODRUGS OF PHARMACEUTICALS WITH IMPROVED BIOAVAILABILITY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-12-19 WO disclosed
WO-1996015132-A1 IMPROVED ANTIVIRAL PRODRUGS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1996-05-23 WO disclosed
US-5187293-A Blood platelet activating factor inhibitors HOFFMANN-LA ROCHE INC. (US) 1993-02-16 US disclosed
US-4847376-A COLORIMETRIC ANALYSIS BOEHRINGER MANNHEIM GMBH (DE) 1989-07-11 US disclosed
EP-0147768-B1 GLYCERIN DERIVATIVES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1989-02-08 EP disclosed
US-4731373-A BLOOD PLATELET ACTIVATING FACTOR HOFFMAN-LA ROCHE INC. (US) 1988-03-15 US disclosed
EP-0094186-B1 GLYCEROL DERIVATIVES, THEIR PRODUCTION AND USE Takeda Chemical Industries, Ltd. (JP) 1986-07-30 EP disclosed
US-4576933-A Method of use of 1-(alkyl for alkylcarbanoyl)-2-carbamoylglycerol derivatives TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1986-03-18 US disclosed
EP-0147768-A2 Glycerin derivatives F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1985-07-10 EP disclosed
EP-0094186-A1 Glycerol derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1983-11-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260109724-A1 ANTIVIRAL COMPOUNDS IRF3, IFNAR1, HAVCR2 USP2 3512/4885TLR2 500/4885CETP 974/4885
US-12594292-B2 Antiviral prodrugs, intermediate-and long-acting formulations and methods ACE2, SARS1, FURIN USP2 1686/4885TLR2 1430/4885CETP 469/4885
US-20080221061-A1 Lung-Targeted Drugs DGKG, GK, PHOSPHO1 USP2 2138/4885TLR2 2784/4885CETP 196/4885
US-12350274-B2 Nucleotide analogs NUDT1, DUT, DPYD USP2 3422/4885TLR2 3556/4885CETP 4700/4885
US-20250177428-A1 ANTIVIRAL PRODRUGS, INTERMEDIATE-AND LONG-ACTING FORMULATIONS AND METHODS SARS1, ACE2, FURIN USP2 1637/4885TLR2 953/4885CETP 360/4885
US-12473314-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 USP2 4298/4885TLR2 3182/4885CETP 85/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.