Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29865611 | 0.81 | HTT (0.50) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL9178607 | 0.81 | ALDH1A1 (0.46) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL30390090 | 0.81 | ALDH1A1 (0.46) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL2207311 | 0.81 | HTT (0.50) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL1559460 | 0.81 | ALDH1A1 (0.44) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL3357119 | 0.79 | ALDH1A1 (0.46) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL30543269 | 0.79 | MAPT (0.40) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL116509 | 0.79 | MAPT (0.40) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL14988555 | 0.79 | KMT2A (0.47) | MAPTPKMALDH1A1KAT2BNPC1 | |
| SCHEMBL3318266 | 0.79 | CTSV (0.48) | MAPTPKMALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012002577-A1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | 富士フイルム株式会社 (JP) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011053697-A1 | 2-AMINOINDOLE COMPOUNDS AND METHODS FOR THE TREATMENT OF MALARIA | GENZYME CORPORATION (US) | 2011-05-05 | — | — | WO | disclosed |