Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30390090 | 1.00 | ALDH1A1 (0.46) | ALDH1A1MAPK1HTTTDP1MAPT | |
| SCHEMBL8986027 | 0.82 | LMNA (0.44) | ALDH1A1MAPK1HTTTDP1MAPT | |
| SCHEMBL29865611 | 0.82 | HTT (0.50) | ALDH1A1HTTTDP1MAPTPKM | |
| SCHEMBL2207311 | 0.82 | HTT (0.50) | ALDH1A1HTTTDP1MAPTPKM | |
| SCHEMBL1559460 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HTTTDP1MAPTPKM | |
| SCHEMBL9983681 | 0.82 | SMN1; SMN2 (0.51) | ALDH1A1MAPK1TDP1MAPTL3MBTL1 | |
| SCHEMBL3357119 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPK1HTTTDP1MAPT | |
| SCHEMBL3368574 | 0.81 | MAPT (0.40) | ALDH1A1HTTTDP1MAPTPKM | |
| SCHEMBL14060514 | 0.81 | PIN1 (0.38) | ALDH1A1MAPK1HTTTDP1MAPT | |
| SCHEMBL8514116 | 0.81 | PIN1 (0.44) | ALDH1A1MAPK1HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12590098-B2 | Pyrimido pyrimidinone compound and pharmaceutical composition comprising the same | AXCESO BIOPHARMA CO., LTD. (KR) | 2026-03-31 | — | — | US | disclosed |
| EP-4215533-B1 | PYRIMIDOPYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | AXCESO BIOPHARMA CO LTD (KR) | 2026-02-11 | — | — | EP | disclosed |
| US-20230348474-A1 | PYRIMIDO PYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | AXCESO BIOPHARMA CO., LTD. (KR) | 2023-11-02 | — | — | US | disclosed |
| EP-4215533-A1 | PYRIMIDOPYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Axceso Biopharma Co., Ltd. (KR) | 2023-07-26 | — | — | EP | disclosed |
| CN-116137815-A | Pyrimidopyrimidinone compounds and pharmaceutical compositions containing the same | 埃克斯索生物制药有限公司 | 2023-05-19 | — | — | CN | disclosed |
| US-5378244-A | Bright blue; colorfastness; hair dyes | KAO CORPORATION (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0559217-A1 | 2-Alkoxy-3,5-diaminopyridine derivatives and their salts, and dye compositions for keratinous fibers containing them | KAO CORPORATION (JP) | 1993-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348474-A1 | PYRIMIDO PYRIMIDINONE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | PDCD1, PDCD1LG2, CD274 | ALDH1A1 443/4885MAPK1 2547/4885HTT 2120/4885 |
| US-12590098-B2 | Pyrimido pyrimidinone compound and pharmaceutical composition comprising the same | PDCD1, CD274, PDCD1LG2 | ALDH1A1 25/4885MAPK1 408/4885HTT 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.