Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 13/20 | 0.36 |
| ▸ | PPARG | P37231 | 12/20 | 0.36 |
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | VDR | P11473 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3293055 | 0.96 | PPARA (0.39) | PPARAPPARGPPARDVDRALDH1A1 | |
| SCHEMBL3368702 | 0.91 | PPARA (0.41) | PPARAPPARGPPARD | |
| SCHEMBL3369298 | 0.88 | PPARA (0.40) | PPARAPPARGPPARD | |
| SCHEMBL3291378 | 0.87 | PPARG (0.41) | PPARAPPARGPPARDVDR | |
| SCHEMBL3314538 | 0.87 | PPARA (0.44) | PPARAPPARGPPARD | |
| SCHEMBL3370894 | 0.86 | PPARG (0.36) | PPARAPPARGPPARDALDH1A1AURKA | |
| SCHEMBL13114663 | 0.84 | VDR (0.49) | PPARAPPARGPPARDVDRALDH1A1 | |
| SCHEMBL3292464 | 0.83 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3295913 | 0.83 | PPARG (0.39) | PPARAPPARGPPARDALDH1A1 | |
| SCHEMBL3370797 | 0.80 | ALDH1A1 (0.48) | PPARAPPARGPPARDVDRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902039-B1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI AVENTIS (FR) | 2010-10-13 | — | — | EP | disclosed |