Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | VDR | P11473 | 3/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3297728 | 0.93 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPK1TSHRHPGD | |
| SCHEMBL3369646 | 0.89 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPK1TSHRHPGD | |
| SCHEMBL3372963 | 0.87 | ALDH1A1 (0.50) | ALDH1A1KDM4EVDRMAPK1TSHR | |
| SCHEMBL13114663 | 0.87 | VDR (0.49) | ALDH1A1KDM4EVDRPPARDMAPK1 | |
| SCHEMBL3293343 | 0.86 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPK1TSHRHPGD | |
| SCHEMBL3291250 | 0.84 | ALDH1A1 (0.54) | ALDH1A1KDM4EVDRMAPK1TSHR | |
| SCHEMBL3368615 | 0.80 | PPARA (0.36) | ALDH1A1VDRPPARDPPARGPPARA | |
| SCHEMBL3373510 | 0.79 | KDM4E (0.49) | ALDH1A1KDM4EVDRPPARDMAPK1 | |
| SCHEMBL3368702 | 0.78 | PPARA (0.41) | PPARDPPARGPPARA | |
| SCHEMBL3372543 | 0.78 | THRB (0.45) | ALDH1A1KDM4ETSHRHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902039-B1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI AVENTIS (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1902039-A1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | Sanofi-Aventis (FR) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007000235-A1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | disclosed |