Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256987 | 0.73 | PGR (0.44) | PGRHTTOPRM1ALDH1A1KDM4E | |
| SCHEMBL10796689 | 0.72 | HTT (0.46) | TSHRHTTKMT2AOPRM1ALDH1A1 | |
| SCHEMBL3368868 | 0.69 | PGR (0.69) | PGRHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL9056337 | 0.69 | PGR (0.44) | TSHRPGRHTTKMT2AALDH1A1 | |
| SCHEMBL68894 | 0.69 | TSHR (0.60) | TSHRHTTKMT2AALDH1A1KDM4E | |
| SCHEMBL68866 | 0.69 | TSHR (0.39) | TSHRHTTOPRM1ALDH1A1KDM4E | |
| SCHEMBL4830158 | 0.68 | PGR (0.50) | TSHRPGRHTTKMT2AALDH1A1 | |
| SCHEMBL11550128 | 0.67 | HTT (0.42) | TSHRHTTKMT2AOPRM1ALDH1A1 | |
| SCHEMBL10199560 | 0.66 | TSHR (0.37) | TSHRHTTALDH1A1HPGD | |
| SCHEMBL568994 | 0.65 | PGR (0.55) | PGRHTTALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | claimed |
| CN-1329365-C | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2007-08-01 | — | — | CN | claimed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | claimed |
| CN-1615294-A | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2005-05-11 | — | — | CN | claimed |
| EP-1340741-A1 | Indane derivatives and their use in perfumery | Givaudan SA (CH) | 2003-09-03 | — | — | EP | claimed |
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-7538243-B2 | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2009-05-26 | — | — | US | disclosed |
| CN-1329365-C | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2007-08-01 | — | — | CN | disclosed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | disclosed |
| CN-1615294-A | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2005-05-11 | — | — | CN | disclosed |
| EP-1340741-A1 | Indane derivatives and their use in perfumery | Givaudan SA (CH) | 2003-09-03 | — | — | EP | disclosed |
| EP-0567953-B1 | Process for the preparation of substituted indanones | HOECHST AG (DE) | 1996-03-13 | — | — | EP | disclosed |
| US-5329049-A | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-07-12 | — | — | US | disclosed |
| EP-0567953-A1 | Process for the preparation of substituted indanones | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | NISCH, CYP1B1, CYP2E1 | TSHR 4768/4885PGR 798/4885HTT 4828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.