Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417754 | 0.87 | PGR (0.77) | PGRKDM4EATMHTTMAOB | |
| SCHEMBL568994 | 0.85 | PGR (0.55) | PGRKDM4EATMHTTMETAP1 | |
| SCHEMBL4421269 | 0.82 | PGR (1.00) | PGRMAOBALDH1A1 | |
| SCHEMBL5648628 | 0.81 | PGR (0.49) | PGRKDM4EATMHTTMETAP1 | |
| SCHEMBL3361527 | 0.79 | PGR (0.55) | PGRKDM4EMETAP1CA1CA2 | |
| SCHEMBL13113557 | 0.79 | PGR (0.55) | PGRKDM4EHTTCYP2C19ALDH1A1 | |
| SCHEMBL388355 | 0.79 | PGR (0.55) | PGRKDM4ECA1CA2CA7 | |
| SCHEMBL192717 | 0.79 | PGR (0.69) | PGRMETAP1MAOBMEN1KMT2A | |
| SCHEMBL20951359 | 0.79 | PGR (0.55) | PGRKDM4EHTTCA9MEN1 | |
| SCHEMBL388758 | 0.77 | PGR (0.53) | PGRKDM4EHTTMETAP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | claimed |
| EP-1478616-A1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | Givaudan SA (CH) | 2004-11-24 | — | — | EP | claimed |
| WO-2003072533-A1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2003-09-04 | — | — | WO | claimed |
| EP-1340741-A1 | Indane derivatives and their use in perfumery | Givaudan SA (CH) | 2003-09-03 | — | — | EP | claimed |
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-7538243-B2 | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2009-05-26 | — | — | US | disclosed |
| EP-1701934-B1 | DISUBSTITUTED CHALCONE OXIMES HAVING RAR(Gamma)-RETINOID RECEPTOR ANTAGONIST ACTIVITY | ALLERGAN INC (US) | 2009-02-25 | — | — | EP | disclosed |
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-20070185057-A1 | Novel Indanone Compounds | SYMRISE GMBH & CO. KG (DE) | 2007-08-09 | — | — | US | disclosed |
| US-7208142-B2 | Indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2007-04-24 | — | — | US | disclosed |
| EP-1341752-B1 | NOVEL INDANYLIDENE COMPOUNDS | SYMRISE GMBH & CO KG (DE) | 2004-08-04 | — | — | EP | disclosed |
| CN-1473146-A | Novel indanylidene compounds | ��������ķ������ | 2004-02-04 | — | — | CN | disclosed |
| EP-1341752-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2003-09-10 | — | — | EP | disclosed |
| EP-1340741-A1 | Indane derivatives and their use in perfumery | Givaudan SA (CH) | 2003-09-03 | — | — | EP | disclosed |
| US-20030125584-A1 | 6-Alkylindan-1-ones as fragrances | SYMRISE GMBH & CO. KG (DE) | 2003-07-03 | — | — | US | disclosed |
| EP-1310240-A1 | 6-Alkylindane-1-ones as perfuming agents | HAARMANN & REIMER GMBH (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-20020143203-A1 | Novel indanylidene compounds | SYMRISE GMBH & CO. KG (DE) | 2002-10-03 | — | — | US | disclosed |
| WO-2002038537-A1 | NOVEL INDANYLIDENE COMPOUNDS | HAARMANN & REIMER GMBH (DE) | 2002-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185057-A1 | Novel Indanone Compounds | CUTA, NISCH, TYR | PGR 3055/4885KDM4E 902/4885ATM 781/4885 |
| US-20030125584-A1 | 6-Alkylindan-1-ones as fragrances | TRPA1, CYP1A1, CYP1B1 | PGR 3883/4885KDM4E 2940/4885ATM 2975/4885 |
| US-20020143203-A1 | Novel indanylidene compounds | CUTA, NISCH, ERCC4 | PGR 3741/4885KDM4E 1177/4885ATM 2286/4885 |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | NISCH, CYP1B1, CYP2E1 | PGR 798/4885KDM4E 2909/4885ATM 2342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.