Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | TDP2 | O95551 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | APAF1 | O14727 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10917714 | 0.76 | MAPT (0.47) | ALDH1A1MAPTTDP2KMT2AAPAF1 | |
| SCHEMBL3369898 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL27796354 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL24355593 | 0.72 | THRB (0.45) | ALDH1A1MAPTTDP2KMT2AAPAF1 | |
| SCHEMBL25698875 | 0.72 | ALDH1A1 (0.53) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL13144527 | 0.71 | THRB (0.46) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL26781883 | 0.71 | ALDH1A1 (0.38) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL27603459 | 0.71 | THRB (0.48) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL29173988 | 0.70 | ALDH1A1 (0.45) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 | |
| SCHEMBL132951 | 0.69 | ALDH1A1 (0.41) | ALDH1A1HSP90AA1HSP90AB1MAPTTDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | claimed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | claimed |
| EP-1478616-B1 | INDANES AND INDANONES AND THEIR USE IN PERFUMERY | GIVAUDAN SA (CH) | 2010-09-22 | — | — | EP | disclosed |
| US-7538243-B2 | Indanes and indanones and their use in perfumery | GIVAUDAN SA (CH) | 2009-05-26 | — | — | US | disclosed |
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | FLACHSMANN FELIX (CH) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050148493-A1 | Indanes and indanones and their use in perfumery | NISCH, CYP1B1, CYP2E1 | ALDH1A1 195/4885HSP90AA1 3088/4885HSP90AB1 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.