SCHEMBL3368936

SCHEMBL3368936

Cc1ccccc1/N=C/c1ccccc1O.[LiH]

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.76
ALDH1A1 P00352 6/20 0.76
KDM4E B2RXH2 5/20 0.76
L3MBTL1 Q9Y468 4/20 0.76
POLB P06746 3/20 0.76
MPI P34949 2/20 0.76
RECQL P46063 1/20 0.76
CA12 O43570 5/20 0.72
CA2 P00918 5/20 0.72
CA9 Q16790 4/20 0.72
ALOX15 P16050 3/20 0.57
PKM P14618 3/20 0.57
THRB P10828 2/20 0.57
CYP2C9 P11712 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP1A2 P05177 1/20 0.57
CYP3A4 P08684 1/20 0.57
CYP2D6 P10635 1/20 0.57
CYP2C19 P33261 1/20 0.57
HIF1A Q16665 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3368939 1.00 MAPT (0.76) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL802042 0.98 MAPT (0.78) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL12566830 0.98 MAPT (0.78) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL1947963 0.98 MAPT (0.78) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL30970907 0.98 MAPT (0.78) MAPTALDH1A1KDM4EL3MBTL1POLB
Lithium SCHEMBL3368945 0.96 MAPT (0.76) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL24440665 0.89 CA12 (0.79) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL3366806 0.88 CA12 (0.66) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL3366812 0.88 CA12 (0.66) MAPTALDH1A1KDM4EL3MBTL1POLB
SCHEMBL3395482 0.87 CA12 (0.96) MAPTALDH1A1KDM4EL3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9437828-B2 Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH (DE) 2016-09-06 US disclosed
US-20150065725-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2015-03-05 US disclosed
US-8883325-B2 Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH (DE) 2014-11-11 US disclosed
US-20120205638-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2012-08-16 US disclosed
US-20100327264-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATNET GMBH (DE) 2010-12-30 US disclosed
EP-2095690-B1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER MERCK PATENT GMBH (DE) 2010-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120205638-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER ACSL3, APOL1, INTS9 MAPT 3539/4885ALDH1A1 2269/4885KDM4E 2810/4885
US-20100327264-A1 ELECTROLUMINESCENT DEVICE USING AZOMETHINE-LITHIUM-COMPLEX AS ELECTRON INJECTION LAYER ACSL3, APOL1, INTS9 MAPT 3581/4885ALDH1A1 2201/4885KDM4E 2786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.