SCHEMBL3369279

SCHEMBL3369279

C[C@H](NC(CCc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.61
ACE P12821 11/20 0.60
TSHR P16473 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5311806 1.00 MME (0.61) MMEACETSHR
SCHEMBL8254252 1.00 MME (0.61) MMEACETSHR
SCHEMBL4668246 1.00 MME (0.61) MMEACETSHR
SCHEMBL5641909 1.00 MME (0.61) MMEACETSHR
SCHEMBL7319806 1.00 MME (0.61) MMEACETSHR
Hydrochloric Acid SCHEMBL10961819 0.98 MME (0.60) MMEACETSHR
Alanine SCHEMBL6415193 0.94 MME (0.56) MMEACE
Homophenylalanine SCHEMBL6419916 0.91 MME (0.53) MMEACE
SCHEMBL8320933 0.90 MME (0.51) MMEACETSHR
Valine SCHEMBL6418604 0.90 MME (0.52) MMEACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1679303-B1 Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative KANEKA CORP (JP) 2010-09-15 EP claimed
EP-1284957-B1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORP (JP) 2008-05-07 EP claimed
EP-1679303-A1 Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative Kaneka Corporation (JP) 2006-07-12 EP claimed
US-7071349-B2 Purification method of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine KANAKA CORPORATION (JP) 2006-07-04 US claimed
EP-0903337-B1 PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES KANEKA CORP (JP) 2006-04-12 EP claimed
EP-1284957-A4 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORP (JP) 2004-12-29 EP claimed
US-20030162991-A1 Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine KANEKA CORPORATION (JP) 2003-08-28 US claimed
EP-1284957-A1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORPORATION (JP) 2003-02-26 EP claimed
WO-2002074728-A1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORPORATION (JP) 2002-09-26 WO claimed
US-6118010-A CATALYTIC REDUCTION OF THE 1-ALKOXYCARBONYL-3-OXO-3-PHENYLPROPYL DERIVATIVE KANEKA CORPORATION (JP) 2000-09-12 US claimed
EP-0903337-A1 PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES KANEKA CORPORATION (JP) 1999-03-24 EP claimed
EP-1679303-B1 Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative KANEKA CORP (JP) 2010-09-15 EP disclosed
US-7375245-B2 N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof EVERLIGHT USA, INC. (US) 2008-05-20 US disclosed
EP-1284957-B1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORP (JP) 2008-05-07 EP disclosed
EP-1679303-A1 Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative Kaneka Corporation (JP) 2006-07-12 EP disclosed
EP-1284957-A1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORPORATION (JP) 2003-02-26 EP disclosed
WO-2002074728-A1 PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE KANEKA CORPORATION (JP) 2002-09-26 WO disclosed
US-6118010-A CATALYTIC REDUCTION OF THE 1-ALKOXYCARBONYL-3-OXO-3-PHENYLPROPYL DERIVATIVE KANEKA CORPORATION (JP) 2000-09-12 US disclosed
EP-0903337-A1 PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES KANEKA CORPORATION (JP) 1999-03-24 EP disclosed
US-5756812-A Process for the preparation of pure (S,S)-N-(1-ethoxycarbonyl-3-phenylpropyl) alanine DSM CHEMIE LINZ GMBH (AT) 1998-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162991-A1 Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine ANPEP, NPEPPS, ADH1A MME 203/4885ACE 308/4885TSHR 4560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.