Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 11/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311806 | 1.00 | MME (0.61) | MMEACETSHR | |
| SCHEMBL8254252 | 1.00 | MME (0.61) | MMEACETSHR | |
| SCHEMBL5641909 | 1.00 | MME (0.61) | MMEACETSHR | |
| SCHEMBL7319806 | 1.00 | MME (0.61) | MMEACETSHR | |
| SCHEMBL3369279 | 1.00 | MME (0.61) | MMEACETSHR | |
| Hydrochloric Acid SCHEMBL10961819 | 0.98 | MME (0.60) | MMEACETSHR | |
| Alanine SCHEMBL6415193 | 0.94 | MME (0.56) | MMEACE | |
| Homophenylalanine SCHEMBL6419916 | 0.91 | MME (0.53) | MMEACE | |
| SCHEMBL8320933 | 0.90 | MME (0.51) | MMEACETSHR | |
| Valine SCHEMBL6418604 | 0.90 | MME (0.52) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284957-B1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2008-05-07 | — | — | EP | claimed |
| US-7071349-B2 | Purification method of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine | KANAKA CORPORATION (JP) | 2006-07-04 | — | — | US | claimed |
| EP-1284957-A4 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2004-12-29 | — | — | EP | claimed |
| US-20030162991-A1 | Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine | KANEKA CORPORATION (JP) | 2003-08-28 | — | — | US | claimed |
| EP-1284957-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2003-02-26 | — | — | EP | claimed |
| WO-2002074728-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2002-09-26 | — | — | WO | claimed |
| US-7375245-B2 | N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof | EVERLIGHT USA, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| EP-1284957-B1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-7071349-B2 | Purification method of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine | KANAKA CORPORATION (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20060009652-A1 | N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof | EVERLIGHT USA, INC. (US) | 2006-01-12 | — | — | US | disclosed |
| EP-1284957-A4 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-20030162991-A1 | Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine | KANEKA CORPORATION (JP) | 2003-08-28 | — | — | US | disclosed |
| EP-1284957-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2003-02-26 | — | — | EP | disclosed |
| WO-2002074728-A1 | PURIFICATION METHOD OF N-(1(S)-ETHOXYCARBONYL-3-PHENYLPROPYL)-L-ALANINE | KANEKA CORPORATION (JP) | 2002-09-26 | — | — | WO | disclosed |
| US-5756812-A | Process for the preparation of pure (S,S)-N-(1-ethoxycarbonyl-3-phenylpropyl) alanine | DSM CHEMIE LINZ GMBH (AT) | 1998-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082496-A1 | ACE-2 modulating compounds and methods of use thereof | ACE, ACE2, AGTR2 | MME 11/4885ACE 1/4885TSHR 2420/4885 |
| US-20030162991-A1 | Purification method of n-(1(s)-ethoxycarbonyl-3-phenylpropyl)-l-alanine | ANPEP, NPEPPS, ADH1A | MME 203/4885ACE 308/4885TSHR 4560/4885 |
| US-20060009652-A1 | N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof | BCAT2, BCAT1, IL4I1 | MME 1172/4885ACE 704/4885TSHR 2803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.