Naphthalene

Naphthalene

SCHEMBL3369808

NC(=O)NC(N)=O.NC(=O)NC(N)=O.c1ccc2ccccc2c1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.50
KDM4E B2RXH2 2/20 0.50
POLB P06746 2/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.44
ALOX12 P18054 1/20 0.44
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
PARP1 P09874 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RECQL P46063 1/20 0.42
BLM P54132 1/20 0.42
PMP22 Q01453 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ALDH1A1 P00352 5/20 0.41
GFER P55789 1/20 0.41
MTNR1A P48039 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Naphthalene SCHEMBL587722 1.00 GAA (0.50) GAAKDM4EPOLBCYP1A2CYP2A6
Naphthalene SCHEMBL2539212 0.89 GAA (0.42) GAAKDM4EPOLBCYP1A2CYP2A6
Naphthalene SCHEMBL4609645 0.82 CYP2A6 (0.57) GAAKDM4EPOLBCYP1A2CYP2A6
Biphenyl SCHEMBL9421865 0.81 LMNA (0.48) GAAPOLBCYP1A2MAPTCYP3A4
Naphthalene SCHEMBL29011577 0.79 CYP2C19 (0.55) GAAKDM4EPOLBCYP1A2CYP2A6
Naphthalene SCHEMBL3359766 0.79 CYP2C19 (0.55) GAAKDM4EPOLBCYP1A2CYP2A6
SCHEMBL1128656 0.79 GAA (0.52) GAAKDM4EPOLBCYP1A2MAPT
SCHEMBL2332052 0.79 GAA (0.52) GAAKDM4EPOLBCYP1A2MAPT
SCHEMBL7463717 0.78 CRBN (0.39) GAAKDM4EPOLBCYP1A2MAPT
Benzil SCHEMBL28364687 0.77 CES2 (0.67) GAAKDM4EPOLBCYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US claimed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US claimed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-8380109-B2 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2013-02-19 US disclosed
US-20100150606-A1 METHOD OF MANUFACTURING IMAGE BEARING MEMBER, IMAGE BEARING MEMBER, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2010-06-17 US disclosed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US disclosed
US-20090180804-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-07-16 US disclosed
US-7498084-B2 Macromolecular structure, functional device having the same, transistor, and display apparatus using the same SHARP KABUSHIKI KAISHA (JP) 2009-03-03 US disclosed
US-20040201018-A1 Polymer structure and functional element having the same, and transistor and display using the same SHARP KABUSHIKI KAISHA (JP) 2004-10-14 US disclosed