Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthalene SCHEMBL29011577 | 0.90 | CYP2C19 (0.55) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL3359766 | 0.90 | CYP2C19 (0.55) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL717001 | 0.87 | BLM (0.50) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL9732717 | 0.86 | ALOX12 (0.42) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL29132366 | 0.84 | SIGMAR1 (0.41) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL587722 | 0.82 | GAA (0.50) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Terephthalamide SCHEMBL7564599 | 0.82 | PARP1 (0.70) | HSD17B10TSHRMAPTTDP1CYP3A4 | |
| Naphthalene SCHEMBL28793702 | 0.82 | CYP2A6 (0.44) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL5180063 | 0.82 | ALOX12 (0.44) | CYP2A6ALOX12HSD17B10TSHRMAPT | |
| Naphthalene SCHEMBL3369808 | 0.82 | GAA (0.50) | CYP2A6ALOX12HSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113507936-A | Encapsulated glycolipid antigens for the treatment of neoplastic disease | 安吉尼科分子传输公司 | 2021-10-15 | — | — | CN | claimed |
| EP-0515523-A4 | USE OF SURAMIN TO TREAT RHEUMATOLOGIC DISEASES | US COMMERCE (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0515523-A1 | USE OF SURAMIN TO TREAT RHEUMATOLOGIC DISEASES | THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) | 1992-12-02 | — | — | EP | claimed |
| WO-1991012009-A1 | USE OF SURAMIN TO TREAT RHEUMATOLOGIC DISEASES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) | 1991-08-22 | — | — | WO | claimed |
| WO-2024124411-A1 | USE OF NAPHTHYLUREA COMPOUNDS IN PREPARATION OF DRUGS FOR TREATING PTERYGIUM | 苏州锐明新药研发有限公司 | 2024-06-20 | — | — | WO | disclosed |
| CN-116731551-B | Environment-friendly paint remover for aviation use and preparation method and application thereof | 广东润和新材料科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-116731551-A | Environment-friendly paint remover for aviation use and preparation method and application thereof | 广东润和新材料科技有限公司 | 2023-09-12 | — | — | CN | disclosed |
| CN-115487183-A | Use of naphthoyl urea compound in preparing medicine for treating pterygium | 苏州锐明新药研发有限公司 | 2022-12-20 | — | — | CN | disclosed |
| CN-113507936-A | Encapsulated glycolipid antigens for the treatment of neoplastic disease | 安吉尼科分子传输公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-110462867-A | Organic electroluminescent device | KONICA MINOLTA INC | 2019-11-15 | — | — | CN | disclosed |
| CN-106133886-B | Semiconductor element and composition for forming insulating layer | 富士胶片株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-109983597-A | Organic electroluminescent device | 柯尼卡美能达株式会社 | 2019-07-05 | — | — | CN | disclosed |
| WO-1998052554-A1 | SPIROCYCLOPROPYL FLUORENES AS MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |
| EP-0718286-B1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL MYERS SQUIBB CO (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1998025606-A1 | BENZODIOXOLE, BENZOFURAN, DIHYDROBENZOFURAN, AND BENZODIOXANE MELATONERGIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-06-18 | — | — | WO | disclosed |
| US-5661185-A | AN ALKOXYPHENYL-ALKYLUREA COMPOUND TREATING SLEEP DISORDER | BRISTOL-MYERS SQUIBB CO. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5541228-A | Melatonergic agents | BRISTOL-MYERS SQUIBB CO. (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0718286-A1 | 3-Alkoxybenzylpiperidine derivatives as melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5530012-A | FOR SLEEP DISORDERS, DEPRESSION, GLAUCOMA, CANCER | BRISTOL-MYERS SQUIBB CO. (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0706994-A1 | Melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-04-17 | — | — | EP | disclosed |