Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL662686 | 0.85 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL12472190 | 0.85 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL661249 | 0.83 | BMPR1B (0.39) | DPP8DPP9DPP7LMNACASP2 | |
| SCHEMBL787397 | 0.81 | DPP8 (0.38) | DPP8DPP9DPP7LMNACA12 | |
| SCHEMBL9106358 | 0.80 | MCL1 (0.47) | LMNACASP2HDAC1HDAC8HDAC6 | |
| SCHEMBL22667214 | 0.76 | BMPR1B (0.52) | BMPR1BBMPR1AACVRL1ACVR1TGFBR1 | |
| SCHEMBL7206240 | 0.75 | BMPR1B (0.36) | DPP8DPP9DPP7LMNACASP2 | |
| SCHEMBL9106355 | 0.74 | NAMPT (0.37) | HDAC1HDAC8HDAC6BMPR1BBMPR1A | |
| SCHEMBL2003570 | 0.74 | P2RX3 (0.42) | HDAC1HDAC8HDAC6HSD17B3KMT2A | |
| SCHEMBL664077 | 0.71 | HDAC1 (0.44) | CASP2HDAC1HDAC8HDAC6HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620399-B1 | INDOLONE-ACETAMIDE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA SA (BE) | 2010-09-22 | — | — | EP | claimed |