Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370058 | 0.77 | LDHA (0.41) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7093065 | 0.70 | HTR2B (0.42) | POLBALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL3372129 | 0.70 | HTR2B (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL7724475 | 0.70 | HTR2B (0.42) | POLBALDH1A1HPGDHSD17B10BCL2L1 | |
| SCHEMBL17459434 | 0.70 | PRKCZ (0.42) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL17404092 | 0.68 | HTR2B (0.35) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL17404616 | 0.68 | HTR2B (0.35) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL15941185 | 0.68 | HTR2B (0.35) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL8303539 | 0.66 | KDM1A (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL8303541 | 0.66 | KDM1A (0.39) | SMN1; SMN2ALDH1A1NPC1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |