Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369371 | 0.84 | TYR (0.37) | ALDH1A1HPGDTSHRMAPT | |
| SCHEMBL3368482 | 0.79 | HPGD (0.40) | HPGDTSHRMAPTTP53PKM | |
| SCHEMBL15423051 | 0.77 | HTR2B (0.43) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL2115910 | 0.71 | KMO (0.44) | ALDH1A1 | |
| SCHEMBL30608416 | 0.70 | HTR2B (0.76) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL26117247 | 0.70 | HTR2B (0.76) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL1534272 | 0.70 | HTR2B (0.76) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL1686982 | 0.70 | HTR2B (0.76) | HTR2BHTR2CALDH1A1HPGDBCL2L1 | |
| SCHEMBL3369845 | 0.70 | SMN1; SMN2 (0.43) | HTR2BALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL3305343 | 0.69 | HTR2B (0.51) | HTR2BHTR2CALDH1A1HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |