Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3761395 | 0.81 | LMNA (0.66) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL3760004 | 0.69 | KDM4E (0.48) | BACE1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL3315939 | 0.68 | BCL2L1 (0.65) | ALDH1A1HPGDCHEK2BCL2L1BAD | |
| SCHEMBL71983 | 0.67 | MCL1 (0.48) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL17668667 | 0.65 | BCL2L1 (0.55) | LMNASCN4AMGLLALDH1A1HPGD | |
| SCHEMBL13977275 | 0.65 | NOTUM (0.53) | KDM4EALDH1A1HSD17B10HPGDBCL2L1 | |
| SCHEMBL6207370 | 0.64 | BCL2L1 (0.54) | LMNAHSD17B10ALOX15BCL2L1BAD | |
| SCHEMBL6289867 | 0.64 | SOS1 (0.58) | LMNASCN4AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL351854 | 0.64 | SOS1 (0.58) | LMNASCN4AKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL6290683 | 0.64 | SOS1 (0.58) | LMNASCN4AKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173169-B1 | ARYL SUBSTITUTED PYRAZOLES, IMIDAZOLES, OXAZOLES, THIAZOLES AND PYRROLES, AND THE USE THEREOF | EURO CELTIQUE SA (LU) | 2010-05-12 | — | — | EP | claimed |