Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | GRN | P28799 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5172834 | 0.85 | MCL1 (0.42) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1663159 | 0.85 | NAMPT (0.44) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL7860405 | 0.84 | NPC1 (0.47) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL5172868 | 0.83 | MCL1 (0.41) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL3277119 | 0.83 | MCL1 (0.41) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL1529724 | 0.83 | MCL1 (0.46) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10937459 | 0.82 | HDAC10 (0.53) | MCL1HSD17B10ALDH1A1POLBTDP1 | |
| SCHEMBL12740590 | 0.81 | MCL1 (0.40) | MCL1KDM4EHSD17B10ALDH1A1HPGD | |
| SCHEMBL10936763 | 0.79 | CXCL8 (0.64) | MCL1ALDH1A1HPGDSMN1; SMN2CXCL8 | |
| SCHEMBL3494614 | 0.79 | HDAC10 (0.40) | MCL1KDM4EHSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778299-A4 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INT BV (NL) | 2009-08-26 | — | — | EP | claimed |
| EP-1778299-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2007-05-02 | — | — | EP | claimed |
| WO-2006096207-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2006-09-14 | — | — | WO | claimed |
| US-20050147555-A1 | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same | BRACCO SUISSE SA (CH) | 2005-07-07 | — | — | US | claimed |
| US-12637563-B2 | Modifiers for polyesters that improve viscosity in melt | KANEKA AMERICAS HOLDING, INC. (US) | 2026-05-26 | — | — | US | disclosed |
| US-20260015444-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2026-01-15 | — | — | US | disclosed |
| WO-2024010749-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| US-20230062748-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2023-03-02 | — | — | US | disclosed |
| CN-115485313-A | Improver for polyesters for improving melt viscosity | 钟化美洲控股公司 | 2022-12-16 | — | — | CN | disclosed |
| WO-2021159009-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | KANEKA AMERICAS HOLDING, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| CN-109415457-B | Method for preparing functionalized polymers | 株式会社普利司通 | 2021-05-25 | — | — | CN | disclosed |
| EP-3099692-B9 | BIFUNCTIONAL CYTOTOXIC AGENTS | PFIZER (US) | 2019-11-13 | — | — | EP | disclosed |
| US-20070191349-A1 | C8, c8' linked 5-oxo-1,2,3,11a-tetrahydro-5h-pyrrolo[2,1-c][1,4] benzodiazepine dimers with 1h-pyrrole-dicarboxylic acid amide linkers and oligomeric analogs therof as well as related compounds for the treatment of proliferative diseases | SPIROGEN LIMITED (GB) | 2007-08-16 | — | — | US | disclosed |
| US-20070191349-A1 | C8, c8' linked 5-oxo-1,2,3,11a-tetrahydro-5h-pyrrolo[2,1-c][1,4] benzodiazepine dimers with 1h-pyrrole-dicarboxylic acid amide linkers and oligomeric analogs therof as well as related compounds for the treatment of proliferative diseases | SPIROGEN LIMITED (GB) | 2007-08-16 | — | — | US | disclosed |
| EP-1778299-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2007-05-02 | — | — | EP | disclosed |
| EP-1720880-A1 | C8, C8' LINKED 5-OXO-1,2,3,11A-TETRAHYDRO-5H-PYRROLO[2,1-C][1,4]BENZODIAZEPINE DIMERS WITH 1H-PYRROLE-DICARBOXYLIC ACID AMIDE LINKERS AND OLIGOMERIC ANALOGS THEREOF AS WELL AS RELATED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Spirogen Limited (GB) | 2006-11-15 | — | — | EP | disclosed |
| WO-2006096207-A2 | METHODS FOR PREPARING MULTIVALENT CONSTRUCTS FOR THERAPEUTIC AND DIAGNOSTIC APPLICATIONS | BRACCO INTERNATIONAL B.V. (NL) | 2006-09-14 | — | — | WO | disclosed |
| WO-2006095234-A2 | INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS | BRACCO IMAGING S.P.A. (IT) | 2006-09-14 | — | — | WO | disclosed |
| WO-2005085250-A1 | C8, C8' LINKED 5-OXO-1,2,3,11A-TETRAHYDRO-5H-PYRROLO[2,1-C][1,4]BENZODIAZEPINE DIMERS WITH 1H-PYRROLE-DICARBOXYLIC ACID AMIDE LINKERS AND OLIGOMERIC ANALOGS THEROF AS WELL AS RELATED COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | SPIROGEN LIMITED (GB) | 2005-09-15 | — | — | WO | disclosed |
| US-20050147555-A1 | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same | BRACCO SUISSE SA (CH) | 2005-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191349-A1 | C8, c8' linked 5-oxo-1,2,3,11a-tetrahydro-5h-pyrrolo[2,1-c][1,4] benzodiazepine dimers with 1h-pyrrole-dicarboxylic acid amide linkers and oligomeric analogs therof as well as related compounds for the treatment of proliferative diseases | TSPO, GABRD, BCOR | MCL1 1329/4885KDM4E 3095/4885HSD17B10 2019/4885 |
| US-20050147555-A1 | Methods for preparing multivalent constructs for therapeutic and diagnostic applications and methods of preparing the same | LDHB, FPGS, MTHFD2 | MCL1 1653/4885KDM4E 2964/4885HSD17B10 718/4885 |
| US-12637563-B2 | Modifiers for polyesters that improve viscosity in melt | CRYAA, INCENP, CRYAB | MCL1 2610/4885KDM4E 2052/4885HSD17B10 384/4885 |
| US-20260015444-A1 | MODIFIERS FOR POLYESTERS THAT IMPROVE VISCOSITY IN MELT | CRYAA, CRYAB, RCC1 | MCL1 2965/4885KDM4E 1991/4885HSD17B10 1930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.