Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3366782 | 0.98 | USP30 (0.52) | USP30HCRTR1HCRTR2HSD11B1DPP4 | |
| SCHEMBL3368239 | 0.89 | ALDH1A1 (0.56) | USP30HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL3368153 | 0.86 | HCRTR1 (0.58) | USP30HCRTR1HCRTR2POLBNPC1 | |
| SCHEMBL3369474 | 0.85 | HCRTR1 (0.47) | USP30HCRTR1HCRTR2DPP4NPC1 | |
| SCHEMBL3370370 | 0.81 | HCRTR1 (0.60) | USP30HCRTR1HCRTR2HSD11B1DPP4 | |
| SCHEMBL3369475 | 0.79 | HCRTR1 (0.61) | USP30HCRTR1HCRTR2HSD11B1DPP4 | |
| SCHEMBL3366778 | 0.79 | HCRTR1 (0.58) | USP30HCRTR1HCRTR2HSD11B1DPP4 | |
| SCHEMBL3366768 | 0.78 | HCRTR1 (0.57) | USP30HCRTR1HCRTR2HSD11B1DPP4 | |
| SCHEMBL4955786 | 0.77 | ALDH1A1 (0.60) | HCRTR1HCRTR2POLBTSHRMAPT | |
| SCHEMBL4955775 | 0.77 | ALDH1A1 (0.60) | HCRTR1HCRTR2POLBTSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532141-B1 | 2-PYRROLIDIN-2-YL- [1,3,4]-OXADIAZOLE DERIVATIVES AND THE USE OF THE SAME AS ANTIDEPRESSANTS | GRUENENTHAL GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |