Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 12/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869789 | 0.88 | STS (0.64) | STSSHBGCA2CA9 | |
| SCHEMBL3374308 | 0.86 | STS (0.52) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL8216010 | 0.86 | STS (0.52) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL3373874 | 0.84 | STS (0.48) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL3371048 | 0.82 | STS (0.46) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL3371053 | 0.82 | STS (0.46) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL7101544 | 0.80 | SHBG (0.52) | STSSHBGHSD17B1ESR1CA2 | |
| SCHEMBL8571107 | 0.79 | SHBG (0.60) | STSSHBGHSD17B1ESR1CYP19A1 | |
| SCHEMBL6130909 | 0.77 | STS (0.48) | STSSHBGESR1CA2CA9 | |
| SCHEMBL8088835 | 0.75 | SHBG (0.54) | STSSHBGHSD17B1ESR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284273-B1 | Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them | STERIX LTD (GB) | 2010-09-29 | — | — | EP | claimed |
| EP-1284273-A2 | Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them | JENAPHARM GmbH (DE) | 2003-02-19 | — | — | EP | claimed |
| EP-1284273-B1 | Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them | STERIX LTD (GB) | 2010-09-29 | — | — | EP | disclosed |
| EP-1284273-A2 | Estra-1,3,5(10)-trien-3-sulfamates a process for their production and pharmaceutical compositions containing them | JENAPHARM GmbH (DE) | 2003-02-19 | — | — | EP | disclosed |