Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 4/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370551 | 1.00 | OXTR (0.65) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3364602 | 0.90 | ALDH1A1 (0.57) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3364599 | 0.90 | ALDH1A1 (0.57) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3365017 | 0.87 | OXTR (0.85) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3365010 | 0.87 | OXTR (0.85) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3396501 | 0.86 | ALDH1A1 (0.54) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3366955 | 0.86 | ALDH1A1 (0.54) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3366952 | 0.86 | ALDH1A1 (0.54) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL5641723 | 0.82 | MEN1 (0.51) | OXTRAVPR1AALDH1A1KDM4EHTT | |
| SCHEMBL3367355 | 0.82 | SMN1; SMN2 (0.54) | OXTRAVPR1AALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335901-B1 | PHARMACEUTICALLY ACTIVE SULFANILIDE DERIVATIVES | MERCK SERONO SA (CH) | 2010-04-14 | — | — | EP | claimed |