SCHEMBL337058

SCHEMBL337058

O=c1cc[nH]c(=O)n1CCCCC(O)O

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TYMP P19971 1/20 0.37
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
PTGER1 P34995 1/20 0.33
PTGER4 P35408 1/20 0.33
PTGER3 P43115 1/20 0.33
HASPIN Q8TF76 1/20 0.32
ADORA2A P29274 2/20 0.31
BRD4 O60885 1/20 0.30
TAF1 P21675 1/20 0.30
BRPF1 P55201 1/20 0.30
CREBBP Q92793 1/20 0.30
CECR2 Q9BXF3 1/20 0.30
BRD9 Q9H8M2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26787539 0.80 ALDH1A1 (0.44) TYMPADRA1DADRA1AADRA1BADORA2A
SCHEMBL4348692 0.78 ADRA1D (0.37) TYMPADRA1DADRA1AADRA1BBRD4
SCHEMBL7099892 0.78 ADORA2A (0.47) ADORA2A
SCHEMBL7181586 0.77 TYMP (0.39) TYMPADRA1DADRA1AADRA1BHASPIN
SCHEMBL16990470 0.77 ADORA2A (0.46) TYMPADORA2A
SCHEMBL10981137 0.77 TYMP (0.39) TYMPADRA1DADRA1AADRA1BHASPIN
SCHEMBL2215261 0.77 HASPIN (0.47) TYMPHASPIN
SCHEMBL17371770 0.76 HASPIN (0.43) TYMPADRA1DADRA1AADRA1BHASPIN
SCHEMBL26037299 0.76 TYMP (0.33) TYMPADRA1DADRA1AADRA1BHASPIN
SCHEMBL10428820 0.75 ADRA1D (0.34) TYMPADRA1DADRA1AADRA1BBRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10427125-B2 Methods for performing patterned chemistry ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-10-01 US disclosed
US-10294526-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2019-05-21 US disclosed
US-10035147-B2 Wafer with gel-based biochips for electrochemical synthesis and electrical detection of polymers INTEL CORPORATION (US) 2018-07-31 US disclosed
US-20170356044-A1 POLYMER CO-LOCATION IN SURFACE-ATTACHED BIOPOLYMERS AND ARRAYS OF BIOPOLYMERS INTEL CORP (US) 2017-12-14 US disclosed
US-9745628-B2 Polymer co-location in surface-attached biopolymers and arrays of biopolymers INTEL CORPORATION (US) 2017-08-29 US disclosed
US-20170234825-A1 HIGH THROUGHPUT BIOCHEMICAL DETECTION USING SINGLE MOLECULE FINGERPRINTING ARRAYS INTEL CORP (US) 2017-08-17 US disclosed
US-9551682-B2 High throughput biochemical detection using single molecule fingerprinting arrays INTEL CORPORATION (US) 2017-01-24 US disclosed
US-20150231633-A1 GEL-BASED BIO CHIP FOR ELECTROCHEMICAL SYNTHESIS AND ELECTRICAL DETECTION OF POLYMERS INTEL CORP (US) 2015-08-20 US disclosed
US-9096953-B2 Method for high throughput, high volume manufacturing of biomolecule micro arrays INTEL CORPORATION (US) 2015-08-04 US disclosed
US-20150212032-A1 METHOD AND APPARATUS FOR MATCH QUALITY ANALYSIS OF ANALYTE BINDING INTEL CORPORATION 2015-07-30 US disclosed
US-5631134-A POSITIONAL SEQUENCING BY HYBRIDIZATION SINGLE STRANDED NUCLEIC ACID TO FORM DETECTORS, LIGATING TARGETS, ISOLATION OF NUCLEIC ACIDS AND HYBRIDIZING NUCLEIC ACIDS THE TRUSTEES OF BOSTON UNIVERSITY (US) 1997-05-20 US disclosed
WO-1997016699-A1 PIEZOELECTRIC FORCE SENSING APPARATUS AND METHODS FOR BIOPOLYMER SEQUENCING TRUSTEES OF BOSTON UNIVERSITY (US) 1997-05-09 WO disclosed
EP-0668932-A4 POSITIONAL SEQUENCING BY HYBRIDIZATION. UNIV BOSTON (US) 1996-11-27 EP disclosed
WO-1996032504-A2 SOLID PHASE SEQUENCING OF BIOPOLYMERS TRUSTEES OF BOSTON UNIVERSITY (US) 1996-10-17 WO disclosed
US-5503980-A DETERMINING NUCLEOTIDE SEQUENCE OF NUCLEIC ACID TARGET USING NUCLEIC ACID PROBES TRUSTEES OF BOSTON UNIVERSITY (US) 1996-04-02 US disclosed
EP-0668932-A1 POSITIONAL SEQUENCING BY HYBRIDIZATION TRUSTEES OF BOSTON UNIVERSITY (US) 1995-08-30 EP disclosed
EP-0439779-B1 Process for producing optically active hydroxy lactones CHISSO CORP (JP) 1995-08-16 EP disclosed
WO-1994011530-A1 POSITIONAL SEQUENCING BY HYBRIDIZATION TRUSTEES OF BOSTON UNIVERSITY (US) 1994-05-26 WO disclosed
US-5084392-A Ester interchange reaction for hydroxy lactones CHISSO CORPORATION (JP) 1992-01-28 US disclosed
EP-0439779-A2 Process for producing optically active hydroxy lactones CHISSO CORPORATION (JP) 1991-08-07 EP disclosed