⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8499928 | 0.73 | — | — | |
| SCHEMBL3353972 | 0.68 | — | — | |
| SCHEMBL28748080 | 0.68 | — | — | |
| SCHEMBL13735602 | 0.65 | FAAH (0.30) | — | |
| SCHEMBL14157628 | 0.65 | — | — | |
| SCHEMBL683343 | 0.64 | — | — | |
| SCHEMBL426377 | 0.63 | FAAH (0.35) | — | |
| SCHEMBL1911588 | 0.60 | NPC1 (0.39) | — | |
| SCHEMBL14152113 | 0.60 | — | — | |
| SCHEMBL21164790 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954274-B1 | SUBSTITUTED QUINOLONES AND METHODS OF USE | CHEMOCENTRYX INC (US) | 2010-11-03 | — | — | EP | disclosed |
| US-7557213-B2 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2009-07-07 | — | — | US | disclosed |
| US-20070167443-A1 | Substituted quinolones and methods of use | CHEMOCENTRYX, INC. (US) | 2007-07-19 | — | — | US | disclosed |