SCHEMBL426377

SCHEMBL426377

CCCC[Sn](CCCC)(CCCC)c1ncco1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.35
CES1 P23141 1/20 0.35
CYP2D6 P10635 3/20 0.31
CYP3A4 P08684 1/20 0.31
CYP1A2 P05177 2/20 0.30
CYP19A1 P11511 2/20 0.30
CYP2C9 P11712 2/20 0.30
CYP2C19 P33261 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13735602 0.88 FAAH (0.30) FAAHCES1
SCHEMBL3353972 0.79
SCHEMBL6416075 0.79 FAAH (0.32) FAAHCES1
SCHEMBL18302641 0.68
SCHEMBL15488269 0.68
SCHEMBL8499928 0.68
SCHEMBL109668 0.67 CYP2D6 (0.34) CYP2D6CYP3A4CYP1A2CYP19A1CYP2C9
SCHEMBL4595010 0.65
SCHEMBL11064389 0.64 TLR8 (0.37) CYP2D6CYP3A4
SCHEMBL859772 0.64 FAAH (0.40) FAAHCES1CYP2D6CYP1A2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1506 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4056574-A1 ACC INHIBITOR AND USE THEREOF Nanjing Ruijie Pharma Co., Ltd. (CN) 2022-09-14 EP claimed
CN-114599654-A ACC inhibitor and application thereof 南京瑞捷医药科技有限公司 2022-06-07 CN claimed
EP-4748837-A1 AROMATIC AMIDE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) 2026-05-27 EP disclosed
EP-4743462-A1 COMPOUNDS COMPRISING A NAPHTHYRIDINE OR PYRIDOPYRIMIDINE CORE AS PTC READ-THROUGH AGENTS Tay Therapeutics Limited (GB) 2026-05-20 EP disclosed
CN-117024411-B Isoquinoline as HPK1 inhibitor 豪夫迈·罗氏有限公司 2026-05-19 CN disclosed
EP-3829559-B1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION MERCK SHARP & DOHME LLC (US) 2026-05-13 EP disclosed
EP-3911640-B1 PCSK9 INHIBITORS FOR USE IN THERAPY, ESPECIALLY THE TREATMENT OF CARDIOVASCULAR DISEASE ASTRAZENECA AB (SE) 2026-05-13 EP disclosed
CN-122010947-A Antagonists of adenosine A2a receptors 阿道尔克斯治疗有限公司 2026-05-12 CN disclosed
US-12617796-B2 Antagonists of the adenosine A2a receptor JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 US disclosed
WO-2026087899-A1 MODULATORS OF THE GPR17 RECEPTOR NXERA PHARMA UK LIMITED (GB) 2026-04-30 WO disclosed
EP-4731207-A2 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS Merck Sharp & Dohme LLC (US) 2026-04-29 EP disclosed
US-5627199-A TREATING SEROTONIN DISORDERS ELI LILLY AND COMPANY (US) 1997-05-06 US disclosed
US-5624944-A SEROTONIN RELATED ILLNESS SUCH AS ANXIETY, DEPRESSION, ANTISECRETORY AGENTS FOR GASTRIC JUICE AND DEMENTIA ELI LILLY AND COMPANY (US) 1997-04-29 US disclosed
US-5594019-A SEROTONIN DISORDERS ELI LILLY AND COMPANY (US) 1997-01-14 US disclosed
US-5364856-A Modification of serotonin function ELI LILLY AND COMPANY (US) 1994-11-15 US disclosed
US-5347013-A FOR TREATING MAMMALS WITH SEROTONIN RELATED DISORDERS ELI LILLY AND COMPANY (US) 1994-09-13 US disclosed
EP-0590971-A1 6-Heterocyclyl-4-amino-1,3,4,5-tetrahydrobenz CD indoles for treating motion sickness and vomiting ELI LILLY AND COMPANY (US) 1994-04-06 EP disclosed
EP-0590970-A1 6-Heterocyclyl-4-amino-1,2,2a,3,4,5-hexahydrobenz CD indoles for treating motion sickness and vomiting ELI LILLY AND COMPANY (US) 1994-04-06 EP disclosed
EP-0506363-A1 6-Heterocyclic-4-amino-1,3,4,5-tetrahydrobenz[cd]indoles ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed
EP-0506369-A1 6-Heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[CD]indoles ELI LILLY AND COMPANY (US) 1992-09-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617796-B2 Antagonists of the adenosine A2a receptor ADORA2A, ADORA2B, ADORA3 FAAH 1457/4885CES1 2644/4885CYP2D6 1078/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.