SCHEMBL33716

SCHEMBL33716

NC(=O)Nc1cccc(N)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDX3X O00571 2/20 0.74
ALDH1A1 P00352 3/20 0.69
MAPT P10636 4/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
HDAC3 O15379 1/20 0.56
HDAC4 P56524 1/20 0.56
HDAC1 Q13547 1/20 0.56
HDAC7 Q8WUI4 1/20 0.56
HDAC2 Q92769 1/20 0.56
HDAC10 Q969S8 1/20 0.56
HDAC11 Q96DB2 1/20 0.56
HDAC8 Q9BY41 1/20 0.56
HDAC6 Q9UBN7 1/20 0.56
HDAC9 Q9UKV0 1/20 0.56
HDAC5 Q9UQL6 1/20 0.56
PTGS1 P23219 3/20 0.54
GAA P10253 2/20 0.52
GFER P55789 2/20 0.52
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521756 1.00 DDX3X (0.74) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
Hydrochloric Acid SCHEMBL30440613 0.98 DDX3X (0.71) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
Hydrochloric Acid SCHEMBL8843870 0.98 DDX3X (0.71) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL29479571 0.98 DDX3X (0.71) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL3690365 0.87 MAPT (0.59) DDX3XALDH1A1MAPTGAAGFER
SCHEMBL28877258 0.85 ALDH1A1 (0.57) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL30314470 0.85 DDX3X (1.00) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL1657499 0.85 DDX3X (1.00) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL1025424 0.83 DDX3X (0.74) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3
SCHEMBL21424258 0.82 DDX3X (0.71) DDX3XALDH1A1MAPTSMN1; SMN2HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2498 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037615-A Photochromic yellow fluorine-containing reactive dye and preparation method and application thereof 湖北丽源科技股份有限公司 2026-05-15 CN claimed
US-12383482-B2 Hair coloring compositions WELLA GERMANY GMBH (DE) 2025-08-12 US claimed
EP-4251285-B1 HAIR COLORING COMPOSITIONS WELLA INT OPERATIONS SWITZERLAND SARL (CH) 2024-09-04 EP claimed
CN-117845656-B Formaldehyde-cleaning antibacterial melamine impregnated paper and preparation method thereof 山东东宇鸿翔装饰材料有限公司 2024-05-24 CN claimed
CN-117845656-A Formaldehyde-cleaning antibacterial melamine impregnated paper and preparation method thereof 山东东宇鸿翔装饰材料有限公司 2024-04-09 CN claimed
US-20240024218-A1 HAIR COLORING COMPOSITIONS WELLA GERMANY GMBH (DE) 2024-01-25 US claimed
CN-117396185-A Hair dyeing composition 威娜国际运营瑞士责任有限公司 2024-01-12 CN claimed
EP-4251285-A1 HAIR COLORING COMPOSITIONS Wella International Operations Switzerland Sàrl (CH) 2023-10-04 EP claimed
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20220183940-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2022-06-16 US claimed
US-20040216244-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and an organic diacid, methods and uses L'OREAL (FR) 2004-11-04 US claimed
US-20040211010-A1 Dye composition comprising a cationic tertiary para-phenylenediamine and a polyol ester, processes therefor and uses thereof L'OREAL (FR) 2004-10-28 US claimed
US-20040205904-A1 Dye composition comprising a cationic tertiary para-phenylenediamine and a vitamin derivative, processes therefor and uses thereof L'OREAL (FR) 2004-10-21 US claimed
US-20040205903-A1 Dyeing composition comprising a cationic pyrrolidine-based para-phenylenefiamine, a tertiary para-phenylenediamine and a benzomorpholine coupler, methods and uses L'OREAL (FR) 2004-10-21 US claimed
EP-0881268-A1 Fiber-reactive triphendioxazine dyes, process for their preparation and the use thereof DyStar Textilfarben GmbH & Co. Deutschland KG (DE) 1998-12-02 EP claimed
EP-0538900-B1 Water-soluble azo compounds, process for their preparation and their use as dyes HOECHST AG (DE) 1997-03-05 EP claimed
US-5292871-A Water-soluble compounds having a fiber-reactive group of the vinyl sulfone monoazo series bonded to an alkanoylamino of benzoylamino grouping, suitable as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1994-03-08 US claimed
CN-1075717-A Benzodiazepine * derivatives YAMANOUCHI PHARMA CO LTD (JP) 1993-09-01 CN claimed
EP-0292825-B1 REACTIVE DYES BAYER AG (DE) 1991-08-07 EP claimed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed