Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 6/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022277 | 0.85 | ACE (0.52) | DPP4DPP8DPP7DPP9FKBP1A | |
| SCHEMBL5720655 | 0.85 | ACE (0.52) | DPP4DPP8DPP7DPP9FKBP1A | |
| SCHEMBL3369568 | 0.85 | ACE (0.52) | DPP4DPP8DPP7DPP9FKBP1A | |
| SCHEMBL3369358 | 0.84 | METAP2 (0.42) | METAP2TSHRPOLB | |
| SCHEMBL5351447 | 0.84 | METAP2 (0.42) | METAP2TSHRPOLB | |
| SCHEMBL3373798 | 0.83 | DPP8 (0.43) | PEPDDPP4DPP8DPP7DPP9 | |
| SCHEMBL12886523 | 0.77 | DPP4 (0.43) | PEPDDPP4DPP8DPP7DPP9 | |
| SCHEMBL1228230 | 0.77 | DPP4 (0.43) | PEPDDPP4DPP8DPP7DPP9 | |
| SCHEMBL3370866 | 0.76 | ACE (0.49) | DPP4DPP8DPP7DPP9FKBP1A | |
| SCHEMBL7275548 | 0.75 | DPP4 (0.47) | DPP4DPP8DPP7DPP9FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1679303-B1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | KANEKA CORP (JP) | 2010-09-15 | — | — | EP | disclosed |
| EP-1679303-A1 | Process for preparing 1-alkoxycarbonyl-3-phenylpropyl derivative | Kaneka Corporation (JP) | 2006-07-12 | — | — | EP | disclosed |
| EP-0903337-B1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORP (JP) | 2006-04-12 | — | — | EP | disclosed |
| EP-0903337-A1 | PROCESS FOR THE PREPARATION OF 1-ALKOXYCARBONYL-3-PHENYLPROPYL DERIVATIVES | KANEKA CORPORATION (JP) | 1999-03-24 | — | — | EP | disclosed |