SCHEMBL33720871

SCHEMBL33720871

CCC(=O)N1CCc2cc(CNC(N)=O)ccc21

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.67
TP53 P04637 8/20 0.66
THRB P10828 2/20 0.66
POLB P06746 4/20 0.65
MAPT P10636 7/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777957 0.75 LMNA (0.48) LMNATP53THRBPOLBMAPT
SCHEMBL19687695 0.74 CYP11B1 (0.56) TP53THRBPOLBMAPT
SCHEMBL23063981 0.74 CYP11B1 (0.56) LMNATP53THRBPOLBMAPT
SCHEMBL27876294 0.73 TP53 (0.53) LMNATP53THRBPOLBMAPT
SCHEMBL8778007 0.72 LMNA (0.50) LMNATP53THRB
SCHEMBL29996161 0.72 CYP11B1 (0.54) LMNATP53THRBPOLBMAPT
SCHEMBL21947215 0.72 NOTUM (0.72) LMNATP53THRBPOLBMAPT
SCHEMBL23063979 0.72 CYP11B1 (0.54) LMNATP53THRBPOLBMAPT
SCHEMBL31253090 0.71 TP53 (0.62) LMNATP53THRBPOLBMAPT
SCHEMBL10154275 0.71 TP53 (0.69) LMNATP53POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121774959-A Application of indolinyl urea compound in preparation of anticancer drugs 昆明医科大学 2026-04-03 CN disclosed