Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784159 | 0.79 | ACHE (0.44) | TP53OPRM1OPRK1OPRD1ACHE | |
| SCHEMBL8777936 | 0.78 | TP53 (0.52) | LMNATP53POLBTHRBMAPT | |
| SCHEMBL8778126 | 0.75 | LMNA (0.48) | LMNATP53POLBMAPT | |
| SCHEMBL33720871 | 0.75 | LMNA (0.67) | LMNATP53POLBTHRBMAPT | |
| SCHEMBL8778095 | 0.74 | FFAR1 (0.47) | LMNATP53POLBMAPT | |
| SCHEMBL10640396 | 0.72 | TP53 (0.53) | LMNATP53MAPT | |
| SCHEMBL9206866 | 0.72 | OPRM1 (0.49) | LMNATP53OPRM1OPRK1OPRD1 | |
| SCHEMBL8778007 | 0.72 | LMNA (0.50) | LMNATP53THRB | |
| SCHEMBL12283585 | 0.72 | ALDH1A1 (0.49) | LMNATP53ACHEMAPT | |
| SCHEMBL29973320 | 0.72 | ALDH1A1 (0.49) | LMNATP53ACHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651743-B1 | INDOLINYL N-HYDROXYUREA AND N-HYDROXAMIC ACID DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1997-12-17 | — | — | EP | disclosed |