SCHEMBL3373283

SCHEMBL3373283

CN(C(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1)c1ccc(-n2cncn2)nc1

nearest known ligand 0.54

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 18/20 0.54
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3343204 0.81 GPR119 (0.55) GPR119
SCHEMBL23410251 0.78 GPR119 (0.67) GPR119
SCHEMBL15377020 0.76 PDE10A (0.49) GPR119
SCHEMBL3373277 0.75 GPR119 (0.48) GPR119
SCHEMBL3373619 0.75 CHEK2 (0.47) GPR119
SCHEMBL2556386 0.75 GPR119 (0.63) GPR119
SCHEMBL2556388 0.75 GPR119 (0.63) GPR119
SCHEMBL23465732 0.74 GPR119 (0.63) GPR119
SCHEMBL3373531 0.73 GPR119 (0.45) GPR119
SCHEMBL12283303 0.73 GPR119 (0.64) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010048149-A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE KALYPSYS, INC. (US) 2010-04-29 WO disclosed