Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3373277 | 0.84 | GPR119 (0.48) | CHEK2GPR119 | |
| SCHEMBL3373531 | 0.83 | GPR119 (0.45) | CHEK2GPR119 | |
| SCHEMBL23410251 | 0.82 | GPR119 (0.67) | CHEK2GPR119 | |
| SCHEMBL3374846 | 0.80 | KCNH2 (0.44) | CHEK2 | |
| SCHEMBL3340657 | 0.80 | GPR119 (0.60) | CHEK2GPR119 | |
| Hydrochloric Acid SCHEMBL3371740 | 0.79 | KCNH2 (0.43) | CHEK2 | |
| SCHEMBL2556388 | 0.78 | GPR119 (0.63) | CHEK2GPR119 | |
| SCHEMBL2556386 | 0.78 | GPR119 (0.63) | CHEK2GPR119 | |
| SCHEMBL3374664 | 0.76 | GPR119 (0.48) | GPR119 | |
| SCHEMBL3373283 | 0.75 | GPR119 (0.54) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |