Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R10 | Q9NYW0 | 2/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.79 |
| ▸ | GLRA1 | P23415 | 15/20 | 0.79 |
| ▸ | GLRB | P48167 | 15/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | SCN1A | P35498 | 1/20 | 0.74 |
| ▸ | TAS2R46 | P59540 | 1/20 | 0.74 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.74 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834780 | 1.00 | TAS2R10 (0.79) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| SCHEMBL30389159 | 0.93 | TAS2R10 (0.79) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL14029321 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL12293782 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL1648976 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL23468158 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL19476145 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL10307298 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| Brucine SCHEMBL29391712 | 0.88 | TAS2R10 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB | |
| SCHEMBL24177883 | 0.88 | GLRA1 (1.00) | TAS2R10CHRM1SMN1; SMN2GLRA1GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1718190-A | Nux vomica alkaloid liposome, and its prepn. method | CAI BAOCHANG (CN) | 2006-01-11 | — | — | CN | claimed |
| US-8765197-B2 | Extract of herbal and composition containing the same | Dong-A-Pharm, Co., Ltd. (KR) | 2014-07-01 | — | — | US | disclosed |
| EP-2206508-B1 | Extract of herbal and the composition containing the same | DONG A ST CO LTD (KR) | 2013-08-21 | — | — | EP | disclosed |
| EP-2206508-A2 | Extract of herbal and the composition containing the same | DONG-A PHARM. CO., LTD. (KR) | 2010-07-14 | — | — | EP | disclosed |
| US-20090186108-A1 | EXTRACT OF HERBAL AND COMPOSITION CONTAINING THE SAME | DONG-A PHARM, CO., LTD. (KR) | 2009-07-23 | — | — | US | disclosed |
| EP-2029150-A1 | EXTRACT OF HERBAL AND THE COMPOSITION CONTAINING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007100203-A1 | EXTRACT OF HERBAL AND THE COMPOSITION CONTAINING THE SAME | DONG-A PHARM. CO., LTD. (KR) | 2007-09-07 | — | — | WO | disclosed |
| CN-1718190-A | Nux vomica alkaloid liposome, and its prepn. method | CAI BAOCHANG (CN) | 2006-01-11 | — | — | CN | disclosed |