Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3371738 | 0.86 | GPR119 (0.60) | GPR119TP53MAPTSMN1; SMN2 | |
| SCHEMBL3373100 | 0.86 | GPR119 (0.52) | GPR119TP53MAPTSMN1; SMN2 | |
| SCHEMBL3374362 | 0.85 | GPR119 (0.52) | GPR119TP53MAPTSMN1; SMN2 | |
| SCHEMBL17104653 | 0.77 | GPR119 (0.62) | GPR119 | |
| SCHEMBL17104649 | 0.77 | GPR119 (0.62) | GPR119 | |
| SCHEMBL13422582 | 0.77 | SMN1; SMN2 (0.42) | TP53MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3374464 | 0.76 | SMN1; SMN2 (0.42) | TP53MAPTSMN1; SMN2 | |
| SCHEMBL3376459 | 0.76 | TP53 (0.48) | GPR119TP53MAPTSMN1; SMN2 | |
| SCHEMBL1118299 | 0.76 | GPR119 (0.77) | GPR119 | |
| SCHEMBL3370707 | 0.74 | GPR119 (0.50) | GPR119SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010048149-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2010-04-29 | — | — | WO | disclosed |