SCHEMBL3373649

SCHEMBL3373649

Nc1cccc(C(=O)CO)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PBRM1 Q86U86 1/20 0.57
NPC1 O15118 1/20 0.49
MITF O75030 1/20 0.49
LMNA P02545 1/20 0.49
POLB P06746 1/20 0.49
F2 P00734 1/20 0.48
PLG P00747 1/20 0.48
PRSS1 P07477 1/20 0.48
PRSS2 P07478 1/20 0.48
PRSS3 P35030 1/20 0.48
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 1/20 0.47
HSD17B10 Q99714 2/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
CYP3A4 P08684 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
KDM4C Q9H3R0 1/20 0.44
CA1 P00915 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL925930 0.98 PBRM1 (0.55) PBRM1NPC1MITFLMNAPOLB
SCHEMBL28359889 0.85 PBRM1 (0.59) PBRM1NPC1MITFLMNAPOLB
SCHEMBL12235278 0.84 TDP1 (0.48) NPC1LMNAF2ALDH1A1KDM4E
SCHEMBL633209 0.83 PBRM1 (0.57) PBRM1NPC1MITFLMNAPOLB
SCHEMBL4331570 0.82 GSK3B (0.57) PBRM1NPC1MITFLMNAPOLB
SCHEMBL7913955 0.82 ACHE (0.56) PBRM1NPC1MITFLMNAPOLB
SCHEMBL7911303 0.82 ALDH1A1 (0.57) PBRM1NPC1MITFLMNAPOLB
SCHEMBL2208370 0.82 PBRM1 (0.55) PBRM1NPC1MITFLMNAPOLB
SCHEMBL1538494 0.80 PBRM1 (0.58) PBRM1NPC1MITFLMNAPOLB
Hydrochloric Acid SCHEMBL27868766 0.80 GSK3B (0.55) PBRM1NPC1MITFLMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 215 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118063344-B Asymmetric enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application XI'AN SHIYOU UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119039328-A Butterfly-shaped trinuclear Schiff base rare earth metal catalyst, preparation method and application 西安石油大学 2024-11-29 CN claimed
CN-119039327-A Symmetrical multidentate Schiff base trinuclear rare earth complex, preparation method and application 西安石油大学 2024-11-29 CN claimed
CN-118950096-A Hourglass-shaped rare earth metal catalyst, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118955323-A Used for Al3+Naphthalene schiff base fluorescent probe for detection, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118955325-A Enhanced single Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-11-15 CN claimed
CN-118878431-A Preparation method of 3-amino-2-hydroxyacetophenone 诚弘制药(威海)有限责任公司 2024-11-01 CN claimed
CN-118206572-A Trinuclear dysprosium single-molecule magnet based on acylhydrazone Schiff base and preparation method 西安石油大学 2024-06-18 CN claimed
CN-118206483-A Enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-06-18 CN claimed
CN-118063344-A Asymmetric enhanced acylhydrazone Schiff base fluorescent probe, preparation method and application 西安石油大学 2024-05-24 CN claimed
CN-106397492-A 2-hydroxyacetophenone derivative Schiff base nickel complex and synthesis method 桂林理工大学 2017-02-15 CN claimed
CN-103880706-A 2-hydroxy-3-(2-hydroxy-3,5-dibromophenylenemethylamine)acetophenone and synthesis method UNIV GUILIN TECH GUT 2014-06-25 CN claimed
CN-103819358-A 2-hydroxy-3-(2-hydroxy-3-methoxyl phenylene methanamine) acetophenone and synthesis method UNIV GUILIN TECH GUT 2014-05-28 CN claimed
CN-103804223-A 2-hydroxy-3-(2-hydroxy-3-ethyoxyl-N-methyl benzene) acetophenone and synthesis method thereof UNIV GUILIN TECH GUT 2014-05-21 CN claimed
CN-101450943-B Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH 2012-11-07 CN claimed
CN-101279903-B Synthetic method of o-hydroxyacetophenone UNIV ZHEJIANG SCIENCE & TECH 2011-11-09 CN claimed
CN-101450943-A Method for synthesizing drug pranlukast from tetrahydrofuran path UNIV HEBEI SCIENCE & TECH (CN) 2009-06-10 CN claimed
CN-101279903-A Synthetic method of o-hydroxyacetophenone UNIV ZHEJIANG SCIENCE & TECH (CN) 2008-10-08 CN claimed
US-7364881-B1 Biological process for the conversion of nitroarenes to ortho-aminophenols using recombinant E. coli strains UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 2008-04-29 US claimed
US-5679859-A TREATING 3-AMINO-2-HYDROXYACETOPHENONE OR HYDROGEN HALIDE SALT THEREOF WITH SULFURIC ACID IN SOLVENT TO IMPROVE BULK DENSITY AND FLOW PROPERTIES SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1997-10-21 US claimed