SCHEMBL3373657

SCHEMBL3373657

CCOP(=O)(Cc1ccc(CP(=O)(OCC)OCC)c(Br)c1)OCC

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EGFR P00533 2/20 0.39
NPY5R Q15761 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.35
TSHR P16473 1/20 0.35
CCNT1 O60563 5/20 0.35
CDK9 P50750 5/20 0.35
HTT P42858 1/20 0.35
HDAC1 Q13547 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3373620 0.83 MAPT (0.44) EGFRPOLBMAPTTSHRCCNT1
SCHEMBL18304415 0.83 PYCR1 (0.39) EGFRMAPTTSHRHTT
SCHEMBL2032181 0.83 HDAC1 (0.42) EGFRNPY5RPOLBMAPTTSHR
SCHEMBL25410896 0.81 KMT2A (0.38) EGFRNPY5RPOLBMAPTTSHR
SCHEMBL13018894 0.79 CCNT1 (0.44) EGFRNPY5RPOLBMAPTCCNT1
SCHEMBL24357667 0.79 BTK (0.35) EGFRNPY5RPOLBMAPTTSHR
SCHEMBL10022793 0.79 MAPT (0.44) EGFRPOLBMAPTTSHRCCNT1
SCHEMBL22462892 0.79 LMNA (0.40) EGFRMAPTHTT
SCHEMBL3375825 0.78 TSHR (0.50) EGFRNPY5RPOLBMAPTTSHR
SCHEMBL19198176 0.78 CCNT1 (0.46) NPY5RPOLBMAPTCCNT1CDK9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2236488-A1 Materials, methods and uses for photochemical generation of acids and/or radical species The Arizona Board of Regents on behalf of the University of Arizona (US) 2010-10-06 EP disclosed
US-7459106-B2 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2008-12-02 US disclosed
US-20050173683-A1 Materials, methods, and uses for photochemical generation of acids and/or radical species THE ARIZ BD OF REGENTS ON BEHALF OF THE UNIV OF AZ (US) 2005-08-11 US disclosed