Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683431 | 1.00 | NOTUM (0.47) | NOTUMLMNASLC6A4CYP1A2CYP3A4 | |
| SCHEMBL10203775 | 0.84 | NOTUM (0.53) | NOTUMSLC6A4CYP1A2CYP3A4MAPK1 | |
| SCHEMBL526316 | 0.84 | NOTUM (0.49) | NOTUMSLC6A4CYP1A2CYP3A4MAPK1 | |
| SCHEMBL10165373 | 0.83 | NOTUM (0.47) | NOTUMSLC6A4CYP1A2CYP3A4MAPK1 | |
| SCHEMBL2870569 | 0.81 | LMNA (0.46) | NOTUMLMNASLC6A4SLC6A2KMT2A | |
| SCHEMBL2182449 | 0.80 | NR3C2 (0.53) | NOTUMSLC6A4CYP1A2CYP3A4MAPK1 | |
| SCHEMBL2006730 | 0.79 | HTR2A (0.48) | LMNASLC6A4SLC6A2KMT2AHTT | |
| SCHEMBL14683256 | 0.78 | KMO (0.44) | SLC6A4SLC6A2 | |
| SCHEMBL14683612 | 0.78 | KMO (0.44) | SLC6A4SLC6A2 | |
| SCHEMBL2007680 | 0.78 | HTR2A (0.49) | SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010047737-A2 | ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (KY) | 2010-04-29 | — | — | WO | disclosed |
| EP-2134721-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | Micurx Pharmaceuticals, Inc. (US) | 2009-12-23 | — | — | EP | disclosed |
| WO-2008108988-A1 | ANTIMICROBIAL HETEROCYCLIC COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS | MICURX PHARMACEUTICALS, INC. (US) | 2008-09-12 | — | — | WO | disclosed |