Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376487 | 0.89 | EPHX2 (0.57) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL27792020 | 0.87 | CYP2C19 (0.49) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL3372136 | 0.82 | CYP3A4 (0.57) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL10936317 | 0.81 | L3MBTL1 (0.49) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL23019311 | 0.77 | CYP3A4 (0.56) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL770934 | 0.77 | CYP3A4 (0.87) | CYP3A4CYP2C19L3MBTL1EPHX2HPGD | |
| SCHEMBL16188288 | 0.77 | ALOX12 (0.59) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| Hydrochloric Acid SCHEMBL5766130 | 0.76 | CYP3A4 (0.54) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| SCHEMBL3376541 | 0.76 | EPHX2 (0.58) | CYP3A4CYP2C19L3MBTL1EPHX2ALOX12 | |
| Oxalic Acid SCHEMBL27880875 | 0.74 | CYP3A4 (0.81) | CYP3A4CYP2C19L3MBTL1EPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | KOWA COMPANY, LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| EP-2172458-A1 | PYRAZOLONE DERIVATIVE | Kowa Company, Ltd. (JP) | 2010-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324091-A1 | Pyrazolone Derivative | SERPINE1, SERPINC1, TFPI | CYP3A4 710/4885CYP2C19 1060/4885L3MBTL1 2165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.