Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.56 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.56 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 2/20 | 0.48 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958258 | 0.85 | CYP2A6 (0.64) | ALDH1A1CYP1A2CYP2C19HTR1ACYP2A6 | |
| SCHEMBL15324073 | 0.85 | CYP2A6 (0.64) | ALDH1A1CYP1A2CYP2C19HTR1ACYP2A6 | |
| SCHEMBL12680440 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CYP1A2CYP2C19HTR1ACYP2A6 | |
| SCHEMBL12478488 | 0.81 | HTR1A (0.56) | ALDH1A1CYP1A2CYP2C19HTR1ACHRNA7 | |
| SCHEMBL29954011 | 0.81 | ALDH1A1 (0.62) | ALDH1A1CYP1A2CYP2C19CYP2A6IMPDH2 | |
| SCHEMBL14216347 | 0.80 | TSHR (0.45) | ALDH1A1CYP1A2HTR1ACYP2A6CHRNA7 | |
| SCHEMBL9732710 | 0.79 | ALDH1A1 (0.56) | ALDH1A1CYP1A2HTR1ACHRNA7HTR2C | |
| SCHEMBL208051 | 0.78 | CAPN1 (0.59) | ALDH1A1CYP1A2CYP2C19CYP2A6IMPDH2 | |
| SCHEMBL351715 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CYP1A2CYP2C19HTR1ACYP2A6 | |
| SCHEMBL671217 | 0.78 | CYP2A6 (0.74) | ALDH1A1CYP1A2CYP2C19CYP2A6IMPDH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113801052-B | Indolylguanidine compound containing aromatic acid ester, and preparation method and application thereof | 西安交通大学 | 2023-06-27 | — | — | CN | claimed |
| CN-113845464-B | Indolyl guanidine compound and preparation method and application thereof | 西安交通大学 | 2023-05-02 | — | — | CN | claimed |
| CN-114981247-A | Piperazine compounds for inhibiting CPS1 | 卫材R&D管理有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-113845464-A | Indolylguanidine compound and preparation method and application thereof | 西安交通大学 | 2021-12-28 | — | — | CN | claimed |
| CN-113801052-A | Indole guanidine compound containing aromatic acid ester and preparation method and application thereof | 西安交通大学 | 2021-12-17 | — | — | CN | claimed |
| CN-121378310-A | Method for constructing near-infrared one-region boron-dipyrromethene dye conjugate through Knoevenagel condensation reaction | 南京理工大学 | 2026-01-23 | — | — | CN | disclosed |
| CN-120019812-A | Artificial toad venom composition and application thereof | 南京中医药大学 | 2025-05-20 | — | — | CN | disclosed |
| CN-118108661-B | Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof | 波米科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118125972-B | Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof | 波米科技有限公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118125972-A | Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof | 波米科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118108661-A | Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof | 波米科技有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-117624062-A | Barbiturates structure-containing compound and preparation method and application thereof | 武汉大学 | 2024-03-01 | — | — | CN | disclosed |
| WO-2014143125-A1 | USE OF INDOLE COMPOUNDS FOR FAT REDUCTION AND SKIN AND SOFT TISSUE TIGHTENING | ALEVERE MEDICAL CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| CN-102786460-A | Synthetic method for indole-3-carboxaldehyde compounds | SUZHOU CHUKAI PHARMACEUTICAL CO LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-102627597-A | Indole-3-carboxaldehyde isobutyryl hydrazone derivatives and preparation method thereof | SHANDONG INST LIGHT INDUSTRY | 2012-08-08 | — | — | CN | disclosed |
| US-8097644-B2 | Indole compounds having sphingosine-1-phosphate (S1P) receptor antagonist | ALLERGAN, INC. (US) | 2012-01-17 | — | — | US | disclosed |
| US-20070232682-A1 | Indole Compounds having sphingosine-1-phosphate (S1P) receptor antagonist | ALLERGAN, INC. (US) | 2007-10-04 | — | — | US | disclosed |
| WO-2007112322-A2 | INDOLE COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST AND/OR ANTAGONIST BIOLOGICAL ACTIVITY | ALLERGAN, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| WO-2006045120-A2 | PURIFICATION OF TEGASEROD MALEATE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2006-04-27 | — | — | WO | disclosed |
| EP-0505322-A1 | Aminoguanidines | SANDOZ LTD. (CH) | 1992-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232682-A1 | Indole Compounds having sphingosine-1-phosphate (S1P) receptor antagonist | S1PR1, S1PR2, S1PR3 | ALDH1A1 2262/4885CYP1A2 2468/4885CYP2C19 2723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.