Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.56 |
| ▸ | HTR2C | P28335 | 9/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.52 |
| ▸ | HTR1D | P28221 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | HTR1B | P28222 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337458 | 0.81 | ALDH1A1 (0.58) | HTR1AHTR2CCHRNA7HTR1DHTR2A | |
| SCHEMBL3741787 | 0.78 | KMT2A (0.56) | HTR1AHTR2CHTR1DHTR2AHTR2B | |
| SCHEMBL6855717 | 0.75 | ALDH1A1 (0.73) | HTR1AHTR2CHTR1DHTR2ACYP2D6 | |
| SCHEMBL664847 | 0.75 | HTR2C (0.53) | HTR1AHTR2CHTR1DHTR2ACYP2D6 | |
| SCHEMBL5259883 | 0.74 | HTR2C (0.56) | HTR1AHTR2CCHRNA7HTR1DHTR2A | |
| SCHEMBL30686491 | 0.74 | HTR2C (0.56) | HTR1AHTR2CCHRNA7HTR1DHTR2A | |
| SCHEMBL5435851 | 0.74 | HTR2C (0.56) | HTR1AHTR2CHTR1DHTR2ACYP2D6 | |
| SCHEMBL1462326 | 0.73 | HTR1A (0.55) | HTR1AHTR2CCHRNA7HTR1DHTR2A | |
| SCHEMBL1462328 | 0.73 | HTR1A (0.55) | HTR1AHTR2CCHRNA7HTR1DHTR2A | |
| SCHEMBL9732710 | 0.73 | ALDH1A1 (0.56) | HTR1AHTR2CCHRNA7HTR1DHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495372-B1 | BORONATED DERIVATIVES FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED TO OXIDATIVE STRESS | UNIV DEGLI STUDI G DANNUNZIO CHIETI PESCARA (IT) | 2021-04-07 | — | — | EP | claimed |
| EP-3495372-A1 | BORONATED DERIVATIVES FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED TO OXIDATIVE STRESS | Universita' Degli Studi G. D Annunzio Chieti - Pescara (IT) | 2019-06-12 | — | — | EP | claimed |
| US-8871718-B2 | Transglutaminase inhibitors and methods of use thereof | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2014-10-28 | — | — | US | claimed |
| US-20130102633-A1 | TRANSGLUTAMINASE INHIBITORS AND METHODS OF USE THEREOF | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2013-04-25 | — | — | US | claimed |
| EP-3495372-B1 | BORONATED DERIVATIVES FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED TO OXIDATIVE STRESS | UNIV DEGLI STUDI G DANNUNZIO CHIETI PESCARA (IT) | 2021-04-07 | — | — | EP | disclosed |
| EP-3495372-A1 | BORONATED DERIVATIVES FOR THE TREATMENT OF DISEASES AND CONDITIONS ASSOCIATED TO OXIDATIVE STRESS | Universita' Degli Studi G. D Annunzio Chieti - Pescara (IT) | 2019-06-12 | — | — | EP | disclosed |
| EP-2678318-A1 | CANNABINOID RECEPTOR MODULATORS | Arena Pharmaceuticals, Inc. (US) | 2014-01-01 | — | — | EP | disclosed |
| WO-2012116279-A1 | CANNABINOID RECEPTOR MODULATORS | ARENA PHARMACEUTICALS, INC. (US) | 2012-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102633-A1 | TRANSGLUTAMINASE INHIBITORS AND METHODS OF USE THEREOF | TGM2, TGM3, TGM1 | HTR1A 3595/4885HTR2C 4128/4885CHRNA7 4772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.