Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21289450 | 0.83 | HTR2B (0.41) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL29390294 | 0.81 | TRPA1 (0.56) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL5335913 | 0.81 | TRPA1 (0.56) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL22361371 | 0.80 | TRPA1 (0.43) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL30228731 | 0.79 | HTR2B (0.39) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL20455655 | 0.79 | HTR2B (0.39) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL21091489 | 0.78 | TDP1 (0.42) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL28493300 | 0.77 | LMNA (0.47) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL2474757 | 0.77 | LMNA (0.47) | HTR2BTRPA1LMNACHRM1SLC6A2 | |
| SCHEMBL25357916 | 0.76 | L3MBTL1 (0.37) | HTR2BTRPA1LMNACHRM1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236488-A1 | Materials, methods and uses for photochemical generation of acids and/or radical species | The Arizona Board of Regents on behalf of the University of Arizona (US) | 2010-10-06 | — | — | EP | disclosed |
| US-4130579-A | Bis(2-methyl-2-cyanopropyl) aromatics | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-19 | — | — | US | disclosed |