SCHEMBL33752

SCHEMBL33752

Cn1ccc2c(O)cccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.54
MAPT P10636 4/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
RHEB Q15382 1/20 0.47
NQO2 P16083 1/20 0.47
HSD11B1 P28845 4/20 0.46
HTR6 P50406 1/20 0.46
TUBB4A P04350 1/20 0.44
TUBB P07437 1/20 0.44
TUBA3C P0DPH7 1/20 0.44
TUBA1B P68363 1/20 0.44
TUBA4A P68366 1/20 0.44
TUBB4B P68371 1/20 0.44
TUBB3 Q13509 1/20 0.44
TUBB2A Q13885 1/20 0.44
TUBB8 Q3ZCM7 1/20 0.44
TUBA3E Q6PEY2 1/20 0.44
TUBA1A Q71U36 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29450529 1.00 HTR2C (0.54) HTR2CMAPTKDM4EALDH1A1RXFP1
Hydrochloric Acid SCHEMBL30359259 0.98 HTR2C (0.53) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL4266761 0.83 HTR2C (0.42) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL29050266 0.82 HTR2C (0.41) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL12309485 0.82 HTR2C (0.42) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL7327382 0.79 HSPA5 (0.52) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL9449964 0.77 TUBB4A (0.54) MAPTKDM4EALDH1A1RXFP1RHEB
SCHEMBL4956866 0.76 HTR2C (0.47) HTR2CMAPTKDM4EALDH1A1HTR6
SCHEMBL256208 0.76 ALDH1A1 (0.50) HTR2CMAPTKDM4EALDH1A1RXFP1
SCHEMBL4951552 0.75 HTR2C (0.47) HTR2CMAPTKDM4EALDH1A1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4121 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20220183940-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2022-06-16 US claimed
EP-3946217-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2022-02-09 EP claimed
US-11013675-B2 Dye composition comprising a para-phenylenediamine oxidation base and a particular coupler L'OREAL (FR) 2021-05-25 US claimed
CN-112089633-A Oxidation dyeing method 莱雅公司 2020-12-18 CN claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
WO-2020201157-A1 DYEING PROCESS USING PEROXYGENATED SALTS AND A SUBSTRATE COMPRISING OXIDATION DYES L'OREAL (FR) 2020-10-08 WO claimed
EP-3687970-A1 PARA-PHENYLENEDIAMINE BASES WITH AN ALIPHATIC CHAINE AND TRIALKYL AMMONIUM GROUP, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES L'Oreal (FR) 2020-08-05 EP claimed
EP-3687978-A1 PARA-PHENYLENEDIAMINE BASES WITH CATIONIC HETEROCYCLES, AND THE USE OF SAME FOR OXIDATION DYEING KERATIN FIBRES L'Oreal (FR) 2020-08-05 EP claimed
CN-111094249-A P-phenylenediamine bases having cationic heterocycles and their use for the oxidation dyeing of keratin fibers 莱雅公司 2020-05-01 CN claimed
WO-1999017728-A1 OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES L'OREAL (FR) 1999-04-15 WO claimed
WO-1998055083-A1 KERATIN FIBRE OXIDATION DYEING COMPOSITION AND DYEING METHOD USING SAME L'OREAL (FR) 1998-12-10 WO claimed
US-5785717-A Composition for the oxidation dyeing of keratin fibers, comprising a diaminopyrazole derivative and a heterocyclic coupler, and dyeing process L'OREAL (FR) 1998-07-28 US claimed
US-5769903-A Composition for the oxidation dyeing of keratin fibers, comprising an oxidation base, an indole coupler and an additional heterocyclic coupler, and dyeing process L'OREAL (FR) 1998-06-23 US claimed
EP-0728464-B1 Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process OREAL (FR) 1997-07-30 EP claimed
CN-1137374-A Composition for oxidation dyeing of keratin fibers, comprising oxidation base, indole coupler and additional heterocyclic coupler, and dyeing process OREAL (FR) 1996-12-11 CN claimed
CN-1137375-A Composition for oxidation dyeing of keratin fibres, comprising at least two oxidation bases and dation be coupler, and dyeing process OREAL (FR) 1996-12-11 CN claimed
EP-0728466-A1 Keratinous fibers oxidation dyeing composition comprising an oxidation base, an indolic coupler and an additional heterocyclic coupler and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
EP-0728464-A1 Composition for dyeing keratinous fibers comprising a diaminopyrazole derivative and a heterocyclic coupleur and dyeing process L'OREAL (FR) 1996-08-28 EP claimed
EP-0728463-A1 Composition for oxidation dyeing of keratinous fibers comprising at least two oxidation bases and an indole coupleur and process for dyeing L'OREAL (FR) 1996-08-28 EP claimed