SCHEMBL337526

SCHEMBL337526

BrCc1c2ccccc2cc2c1ccc1ccccc12.[CH]

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
HSD17B10 Q99714 4/20 0.54
CYP1B1 Q16678 2/20 0.54
HIF1A Q16665 1/20 0.54
HPRT1 P00492 4/20 0.46
CYP2A6 P11509 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR2A P28223 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CYP1A2 P05177 6/20 0.40
FYN P06241 2/20 0.40
ACHE P22303 2/20 0.40
AHR P35869 2/20 0.40
CYP2C9 P11712 2/20 0.40
CYP2C19 P33261 2/20 0.40
ERBB2 P04626 1/20 0.40
MAOA P21397 1/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL83486 0.98 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL29516177 0.82 HTR2A (0.60) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL118514 0.82 HTR2A (0.60) ALDH1A1HSD17B10CYP1B1HIF1ACYP2A6
SCHEMBL3343719 0.79 ALDH1A1 (0.56) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL19065039 0.79 L3MBTL1 (0.70) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL5665402 0.78 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL2312432 0.76 ALDH1A1 (0.52) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL12627467 0.75 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL14559256 0.75 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1
SCHEMBL17183136 0.75 ALDH1A1 (0.54) ALDH1A1HSD17B10CYP1B1HIF1AHPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097405-B1 Nucleic acid sequencing processes using non-radioactive detectable modified or labeled nucleotides or nucleotide analogs, and other processes for nucleic acid detection and chromosomal characterization using such non-radioactive detectable modified or labeled nucleotides or nucleotide analogs ENZO BIOCHEM, INC. (US) 2012-01-17 US disclosed
US-7220854-B1 Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2007-05-22 US disclosed
US-6992180-B1 Oligo- or polynucleotides comprising phosphate-moiety labeled nucleotides ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2006-01-31 US disclosed
EP-0286898-B1 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM INC (US) 1998-04-29 EP disclosed
EP-0618228-A1 Protein with a moiety capable of chelating ions attached thereto ENZO BIOCHEM, INC. (US) 1994-10-05 EP disclosed
US-5260433-A Nonradioactive ENZO DIAGNOSTICS, INC. (US) 1993-11-09 US disclosed
US-5241060-A Base moiety-labeled detectable nucleatide ENZO DIAGNOSTICS, INC. (US) 1993-08-31 US disclosed
EP-0302175-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1989-02-08 EP disclosed
EP-0286898-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1988-10-19 EP disclosed
EP-0285950-A2 A drug delivery conjugate ENZO BIOCHEM, INC. (US) 1988-10-12 EP disclosed
EP-0285058-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1988-10-05 EP disclosed
EP-0285057-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1988-10-05 EP disclosed
EP-0097373-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1984-01-04 EP disclosed