Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 2/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380618 | 0.83 | PRCP (0.47) | CACNA1GMCHR1PRCPTACR1 | |
| Hydrochloric Acid SCHEMBL22607752 | 0.81 | SIRT2 (0.46) | CACNA1GKCNH2SIRT2SIRT1SCN3A | |
| SCHEMBL3375549 | 0.74 | MC4R (0.39) | TRPM8MC4R | |
| Hydrochloric Acid SCHEMBL28626980 | 0.74 | SIRT2 (0.44) | KCNH2SIRT2SIRT1MAOB | |
| SCHEMBL3378694 | 0.71 | MCHR1 (0.46) | KCNH2MCHR1PRCP | |
| SCHEMBL3345498 | 0.70 | RORC (0.57) | KCNH2MC4R | |
| SCHEMBL9556728 | 0.69 | CACNA1G (0.54) | CACNA1GMAOB | |
| SCHEMBL3346208 | 0.69 | RORC (0.58) | MC4RMCHR1MAOB | |
| SCHEMBL22398100 | 0.68 | FFAR1 (0.53) | KCNH2CYP1A2MAOBCYP2C19 | |
| SCHEMBL18685562 | 0.67 | NTRK1 (0.51) | MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059922-A1 | PYRROLIDINE CARBOXAMIDE COMPOUNDS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2010-05-27 | — | — | WO | claimed |