SCHEMBL3376374

SCHEMBL3376374

COc1cc(O)c(O)c(CN(CC(=O)O)CC(=O)O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ABL1 P00519 1/20 0.50
MAPT P10636 1/20 0.50
RECQL P46063 1/20 0.50
RIN1 Q13671 1/20 0.50
CTDSP1 Q9GZU7 1/20 0.50
PRKCE Q02156 1/20 0.40
HSD17B10 Q99714 1/20 0.40
CYP3A4 P08684 4/20 0.39
TSHR P16473 2/20 0.39
BACE1 P56817 1/20 0.39
PTGES O14684 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP19A1 P11511 1/20 0.38
CYP2C9 P11712 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3377946 0.87 POLB (0.47) POLBKDM4EABL1MAPTRECQL
SCHEMBL18359693 0.79 HIF1A (0.47) POLBKDM4EABL1MAPTRECQL
SCHEMBL3376720 0.79 SELL (0.43) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL3374937 0.76 ALOX15 (0.41) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL30371189 0.76 ALDH1A1 (0.54) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL3371904 0.76 HSD17B10 (0.42) KDM4EHSD17B10TSHRTDP1CYP2C9
SCHEMBL3371928 0.76 ALDH1A1 (0.54) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL3372548 0.74 HSD17B10 (0.36) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL10809043 0.73 ALDH1A1 (0.46) POLBKDM4EMAPTRECQLHSD17B10
SCHEMBL17714020 0.73 TSHR (0.57) POLBKDM4EMAPTTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010079409-A2 USE OF AMINOCARBOXYLATE FUNCTIONALIZED CATECHOLS FOR CLEANING APPLICATIONS ECOLAB INC. (US) 2010-07-15 WO disclosed
US-7645731-B1 Use of aminocarboxylate functionalized catechols for cleaning applications ECOLAB INC. (US) 2010-01-12 US disclosed