SCHEMBL3371904

SCHEMBL3371904

O=C(O)CN(CC(=O)O)Cc1cc(Cl)cc(O)c1O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
HIF1A Q16665 2/20 0.39
CYP2C9 P11712 3/20 0.36
CYP2C19 P33261 3/20 0.36
ALOX15 P16050 2/20 0.36
EGFR P00533 2/20 0.35
ERBB2 P04626 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MEP1A Q16819 1/20 0.35
MEP1B Q16820 1/20 0.35
TDP1 Q9NUW8 2/20 0.34
EYA2 O00167 1/20 0.34
APP P05067 1/20 0.34
ACE P12821 1/20 0.34
AKR1C4 P17516 1/20 0.34
AKR1C3 P42330 1/20 0.34
AKR1C2 P52895 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3377925 0.85 TDP1 (0.39) HSD17B10ALDH1A1HPGDHIF1ACYP2C19
SCHEMBL30371189 0.79 ALDH1A1 (0.54) HSD17B10ALDH1A1HPGDCYP2C9ALOX15
SCHEMBL3376720 0.79 SELL (0.43) HSD17B10ALDH1A1HPGDHIF1ACYP2C9
SCHEMBL3371928 0.79 ALDH1A1 (0.54) HSD17B10ALDH1A1HPGDCYP2C9ALOX15
SCHEMBL545517 0.77 ALOX15 (0.50) HSD17B10ALDH1A1HPGDHIF1ACYP2C9
SCHEMBL3374937 0.77 ALOX15 (0.41) HSD17B10ALDH1A1HPGDHIF1ACYP2C9
SCHEMBL3376374 0.76 POLB (0.50) HSD17B10HPGDCYP2C9CYP2C19TDP1
SCHEMBL3372548 0.74 HSD17B10 (0.36) HSD17B10ALDH1A1HIF1ACYP2C9ALOX15
SCHEMBL8543249 0.74 ALDH1A1 (0.43) HSD17B10ALDH1A1HIF1ACYP2C19ALOX15
SCHEMBL10809043 0.73 ALDH1A1 (0.46) HSD17B10ALDH1A1HPGDHIF1ACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010079409-A2 USE OF AMINOCARBOXYLATE FUNCTIONALIZED CATECHOLS FOR CLEANING APPLICATIONS ECOLAB INC. (US) 2010-07-15 WO disclosed
US-7645731-B1 Use of aminocarboxylate functionalized catechols for cleaning applications ECOLAB INC. (US) 2010-01-12 US disclosed